NCT00561561|Completed
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Sponsor study identifier
interventional
531
1 country
1
Study Start
June 2001
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
August 26, 2011
Actual (reported)Study Completion
August 26, 2011
Actual (reported)This study is looking at problems people sometimes have taking in information from their senses. Specifically, we are comparing the way in which people diagnosed with schizophrenia process sound information, compared with people who have never been diagnosed with a psychiatric disorder. When people hear a loud sound they sometimes feel startled, and when they feel startled they usually blink their eyes. However, if they hear a softer sound shortly before the loud one they may not blink their eyes - in other words, the eye-blink response is smaller. When this happens it's called prepulse inhibition of startle. In this study, we want to measure the startle response and prepulse inhibition of startle in individuals diagnosed with schizophrenia versus individuals not diagnosed with schizophrenia. We also want to find out whether people show the same amount of prepulse inhibition of startle as other members of their family.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
August 26, 2011
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Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
June 2001
Date type not reportedThis date has not been verified as actual or estimated.
November 20, 2007
Actual (reported)November 21, 2007
Actual (reported)August 26, 2011
Actual (reported)August 26, 2011
Actual (reported)Prepulse inhibition of acoustic startle
Day 1 Post-intervention
Subjects with schizophrenia
Health controls
Family members of subjects with schizophrenia
recording of eyeblink component of acoustic startle reflex with small surface electrodes during presentation of acoustic stimuli through headphones
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Atlanta VA Medical Center
Decatur, Georgia, 30033, United States
Erica Duncan, MD
Atlanta VA Medical Center, Emory University Dept of Psychiatry & Behavioral Sciences
531 participants (actual enrollment reported by the registry).
First Submitted
November 20, 2007
First Posted
November 21, 2007
Study Start
June 2001
Date type not reportedThis date has not been verified as actual or estimated.
Antidepressant Treatment in Older Adults With Schizophrenia
Family members of healthy controls
Contact the study team to confirm eligibility.
Primary Completion
August 26, 2011
Actual (reported)Study Completion
August 26, 2011
Actual (reported)Last Updated
August 7, 2019
Record last verified: 2019-08
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Source: ClinicalTrials.gov.
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