A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging

NCT00556114 | Completed

• 1 other identifier: 20043555
• Study Type: observational
• Target: 23
• Locations: 1 country
• Sites: 1

Brief Summary

Growing evidence shows that altered blood flow plays a major role in many vision-threatening diseases including glaucoma, diabetic retinopathy, age-related macular degeneration, Central Retinal Vein Occlusion, and Branch Retinal Vein Occlusion. Optical coherence tomography, an established imaging technique use for eye exam in clinical ophthalmology, provides high-resolution cross sectional images of the retina and has increased our ability to understand many eye diseases.

Conditions

Glaucoma; Diabetic Retinopathy; Age-Related Macular Degeneration; Central Retinal Vein Occlusion; Branch Retinal Vein Occlusion

Keywords

eye exam; Retina

Outcome Measures

Primary Outcomes (1)

• Medical exam tool

  Optical Coherence Tomography imaging technique of the retina and ability to diagnose and manage many eye diseases

  24 hours

Study Arms (1)

Optical Coherence Tomography

Optical Coherence Tomography

Device: Optical Coherence Tomography

Interventions

Optical Coherence Tomography DEVICE

Optical Coherence Tomography

Optical Coherence Tomography

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Primary care clinic and community sample.

You may qualify if:

• Adult 18 years and older with normal eye, or has been diagnosed with eye disease.

You may not qualify if:

• Less than 18 years of age.

Sponsors & Collaborators

• University of California, Irvine: lead
• Beckman Laser Institute University of California Irvine: collaborator

Study Sites (1)

Beckman Laser Institute, University of California,Irvine

Irvine, California, 02612, United States

Location

MeSH Terms

Conditions

Glaucoma; Diabetic Retinopathy; Macular Degeneration; Retinal Vein Occlusion

Interventions

Tomography, Optical Coherence

Condition Hierarchy (Ancestors)

Ocular Hypertension; Eye Diseases; Retinal Diseases; Diabetic Angiopathies; Vascular Diseases; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus; Endocrine System Diseases; Retinal Degeneration; Venous Thrombosis; Thrombosis; Embolism and Thrombosis

Intervention Hierarchy (Ancestors)

Tomography, Optical; Optical Imaging; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Tomography; Investigative Techniques

Study Officials

• Baruch D Kuppermann,, M.D., Ph.D.

  Ophthamology, University of California,Irvine

  PRINCIPAL INVESTIGATOR

• Zhongping Chen, Ph,D

  Beckman Laser Institute University of California Irvine

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Baruch D. Kuppermann, M.D., Ph.D.,Professor Department of Ophthalmology and Biomedical Engineering

Study Record Dates

• First Submitted: November 7, 2007
• First Posted: November 9, 2007
• Study Start: January 1, 2007
• Primary Completion: July 1, 2013
• Study Completion: July 1, 2013
• Last Updated: October 20, 2022

Record last verified: 2022-10

Locations

US (1)