Key Insights

Highlights

Success Rate

85% trial completion

Published Results

77 trials with published results (19%)

Research Maturity

217 completed trials (55% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

9.8%

39 terminated out of 396 trials

Success Rate

84.8%

-1.7% vs benchmark

Late-Stage Pipeline

14%

54 trials in Phase 3/4

Results Transparency

35%

77 of 217 completed with results

Key Signals

77 with results85% success39 terminated

Data Visualizations

Phase Distribution

280Total
Not Applicable (102)
Early P 1 (4)
P 1 (59)
P 2 (61)
P 3 (29)
P 4 (25)

Trial Status

Completed217
Unknown57
Recruiting44
Terminated39
Active Not Recruiting20
Withdrawn9

Trial Success Rate

84.8%

Benchmark: 86.5%

Based on 217 completed trials

Clinical Trials (396)

Showing 20 of 20 trials
NCT01866371Recruiting

High Resolution Retinal Imaging

NCT06662162Not ApplicableRecruitingPrimary

Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration

NCT06961370Phase 1Recruiting

A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

NCT07496567Phase 2Recruiting

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)

NCT07440225Phase 2Recruiting

A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)

NCT00594672Active Not RecruitingPrimary

Age-Related Eye Disease Study (AREDS) Follow-Up

NCT05536297Phase 3Completed

Avacincaptad Pegol Open-Label Extension for Patients With Geographic Atrophy

NCT07015034Not ApplicableRecruiting

Developing and Testing a Model to Identify Preventive Vision Loss Among Older Patients in General Practice

NCT07556406RecruitingPrimary

Central micrOperimetry and Radial OCT Evaluation in Geographic Atrophy (CORE-GA): a Prospective Pilot Study

NCT07555574Not ApplicableRecruitingPrimary

Defining Retinal Structures Using Hyperspectral Retinal Imaging

NCT02286089Phase 1Active Not RecruitingPrimary

Safety and Efficacy Study of OpRegen for Treatment of Advanced Dry-Form Age-Related Macular Degeneration

NCT07550504Phase 2CompletedPrimary

A Study to Evaluate the Usability of the SB11 PFS in Trial Participants With Wet AMD, Macular Oedema Secondary to RVO, or mCNV

NCT03225131Active Not RecruitingPrimary

Dark Adaptation in Participants With Age-Related Macular Degeneration

NCT03848663Not ApplicableRecruitingPrimary

Visual Remapping to Aid Reading With Field Loss

NCT05112861Phase 3Active Not RecruitingPrimary

A 3-month Study to Compare the Safety of ONS-5010 in Vials Versus Pre-filled Syringe in Subjects With Visual Impairment Due to Retinal Disorders

NCT01352975Active Not RecruitingPrimary

Study of Dark Adaptation in Age-Related Macular Degeneration

NCT03092492CompletedPrimary

AMD Ryan Initiative Study (ARIS)

NCT01496625RecruitingPrimary

National Eye Institute Biorepository for Retinal Diseases

NCT06924021RecruitingPrimary

Age-Related Macular Degeneration Benchmark Imaging Dataset (ABID)

NCT02941263CompletedPrimary

Natural History of Geographic Atrophy Associated With Age-Related Macular Degeneration

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Research Network

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