3 Screen Electronic Alert

NCT00550082 | Completed

• 1 other identifier: 2006-P-002346
• Study Type: observational
• Target: 880
• Locations: 1 country
• Sites: 1

Brief Summary

Evaluation of physician responses to BICS-Clinical Information 3-screen alerts that informs the clinician that his/her patient may be eligible for thromboprophylaxis.

Conditions

Deep Vein Thrombosis; Pulmonary Embolism; Cancer

Keywords

Anticoagulation; High-Risk; Deep Vein Thrombosis; Pulmonary Embolism; Surgery

Outcome Measures

Primary Outcomes (1)

• Venous Thromboembolism and Bleeding Events

  90 Days

Secondary Outcomes (2)

• Re-hospitalization

  90 Days

• Mortality

  30 Days

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Hospitalized patients at Brigham and Women's Hospital from medical and surgical services who are 18 yrs old or older and are at a moderate to high risk for venous thromboembolism (VTE)

You may qualify if:

• Hospitalized patients at Brigham and Women's Hospital from medical and surgical services who are 18 yrs old or older and are at a moderate to high risk for venous thromboembolism (VTE)

Sponsors & Collaborators

• Brigham and Women's Hospital: lead
• Eisai Inc.: collaborator

Study Sites (1)

Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States

Location

Related Publications (12)

• Parasuraman S, Goldhaber SZ. Venous thromboembolism in children. Circulation. 2006 Jan 17;113(2):e12-6. doi: 10.1161/CIRCULATIONAHA.105.583773. No abstract available.

  PMID: 16418440 BACKGROUND

• Piazza G, Goldhaber SZ. Acute pulmonary embolism: part II: treatment and prophylaxis. Circulation. 2006 Jul 18;114(3):e42-7. doi: 10.1161/CIRCULATIONAHA.106.620880. No abstract available.

  PMID: 16847156 BACKGROUND

• Piazza G, Goldhaber SZ. Acute pulmonary embolism: part I: epidemiology and diagnosis. Circulation. 2006 Jul 11;114(2):e28-32. doi: 10.1161/CIRCULATIONAHA.106.620872. No abstract available.

  PMID: 16831989 BACKGROUND

• Geerts WH, Pineo GF, Heit JA, Bergqvist D, Lassen MR, Colwell CW, Ray JG. Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004 Sep;126(3 Suppl):338S-400S. doi: 10.1378/chest.126.3_suppl.338S.

  PMID: 15383478 BACKGROUND

• Paterno MD, Cina JL, Goldhaber SZ, Kucher N. Preventing DVT and PE in hospitalized patients: improving a successful electronic alert. AMIA Annu Symp Proc. 2006;2006:1058.

  PMID: 17238677 BACKGROUND

• Kucher N, Goldhaber SZ. Risk stratification of acute pulmonary embolism. Semin Thromb Hemost. 2006 Nov;32(8):838-47. doi: 10.1055/s-2006-955466.

  PMID: 17171598 BACKGROUND

• Kucher N, Koo S, Quiroz R, Cooper JM, Paterno MD, Soukonnikov B, Goldhaber SZ. Electronic alerts to prevent venous thromboembolism among hospitalized patients. N Engl J Med. 2005 Mar 10;352(10):969-77. doi: 10.1056/NEJMoa041533.

  PMID: 15758007 BACKGROUND

• Goldhaber SZ, Dunn K, MacDougall RC. New onset of venous thromboembolism among hospitalized patients at Brigham and Women's Hospital is caused more often by prophylaxis failure than by withholding treatment. Chest. 2000 Dec;118(6):1680-4. doi: 10.1378/chest.118.6.1680.

  PMID: 11115458 BACKGROUND

• Goldhaber SZ, Turpie AG. Prevention of venous thromboembolism among hospitalized medical patients. Circulation. 2005 Jan 4;111(1):e1-3. doi: 10.1161/01.CIR.0000150393.51958.54. No abstract available.

  PMID: 15630031 BACKGROUND

• Goldhaber SZ, Tapson VF; DVT FREE Steering Committee. A prospective registry of 5,451 patients with ultrasound-confirmed deep vein thrombosis. Am J Cardiol. 2004 Jan 15;93(2):259-62. doi: 10.1016/j.amjcard.2003.09.057.

  PMID: 14715365 BACKGROUND

• Cushman M, Tsai AW, White RH, Heckbert SR, Rosamond WD, Enright P, Folsom AR. Deep vein thrombosis and pulmonary embolism in two cohorts: the longitudinal investigation of thromboembolism etiology. Am J Med. 2004 Jul 1;117(1):19-25. doi: 10.1016/j.amjmed.2004.01.018.

  PMID: 15210384 BACKGROUND

• Anderson FA Jr, Wheeler HB, Goldberg RJ, Hosmer DW, Patwardhan NA, Jovanovic B, Forcier A, Dalen JE. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study. Arch Intern Med. 1991 May;151(5):933-8.

  PMID: 2025141 BACKGROUND

Related Links

• North American Thrombosis Forum (NATF)

MeSH Terms

Conditions

Venous Thrombosis; Pulmonary Embolism; Neoplasms

Condition Hierarchy (Ancestors)

Thrombosis; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases; Lung Diseases; Respiratory Tract Diseases; Embolism

Study Officials

• Samuel Z Goldhaber, MD

  Brigham and Women's Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director, VTE Research Group

Study Record Dates

• First Submitted: October 24, 2007
• First Posted: October 26, 2007
• Study Start: July 1, 2007
• Primary Completion: November 1, 2009
• Study Completion: November 1, 2009
• Last Updated: February 10, 2012

Record last verified: 2012-02

Locations

US (1)