Optical Biopsy of Human Skin in Conjunction With Laser Treatment

NCT00540566 | Completed

• 1 other identifier: 1996200
• Study Type: observational
• Target: 113
• Locations: 1 country
• Sites: 1

Brief Summary

This study is to compare the ability of optical biopsy. Research can use light enters the skin, collected, analyzed by the computer, and a picture created for the pathologist to conventional histologic examination compare with the pathologist looking at the piece of tissue through a microscope makes the diagnosis.

Conditions

Malignant Melanoma; Merkel Cell Carcinoma; Basal Cell Carcinoma; Squamous Cell Carcinoma; Atypical Nevi; Congenital Nevi; Seborrheic Keratosis; Paget's Disease; Dermatofibroma; Kaposi's Sarcoma; Port Wine Stain; Hemangioma; Tattoos; Scleroderma; Burns

Outcome Measures

Primary Outcomes (1)

• normal skin

  12 weeks

Study Arms (1)

Optical Biopsy

Optical Biopsy imaging

Device: Optical Biopsy imaging

Interventions

Optical Biopsy imaging DEVICE

Optical Biopsy imaging

Optical Biopsy

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

primary care clinic, community sample

You may qualify if:

• Male or female age \> 18 years

You may not qualify if:

• current participation in any other investigational drug evaluation
• inability to understand and carry out instructions

Sponsors & Collaborators

• University of California, Irvine: lead
• Beckman Laser Institute University of California Irvine: collaborator

Study Sites (1)

Beckman Laser Institute, Unversity of California Irvine

Irvine, California, 92612, United States

Location

MeSH Terms

Conditions

Melanoma; Carcinoma, Merkel Cell; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dysplastic Nevus Syndrome; Keratosis, Seborrheic; Osteitis Deformans; Histiocytoma, Benign Fibrous; Sarcoma, Kaposi; Port-Wine Stain; Hemangioma; Scleroderma, Diffuse; Burns

Condition Hierarchy (Ancestors)

Neuroendocrine Tumors; Neuroectodermal Tumors; Neoplasms, Germ Cell and Embryonal; Neoplasms by Histologic Type; Neoplasms; Neoplasms, Nerve Tissue; Nevi and Melanomas; Skin Neoplasms; Neoplasms by Site; Skin Diseases; Skin and Connective Tissue Diseases; Polyomavirus Infections; DNA Virus Infections; Virus Diseases; Infections; Tumor Virus Infections; Carcinoma, Neuroendocrine; Adenocarcinoma; Carcinoma; Neoplasms, Glandular and Epithelial; Neoplasms, Basal Cell; Neoplasms, Squamous Cell; Nevus; Neoplastic Syndromes, Hereditary; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Keratosis; Bone Diseases; Musculoskeletal Diseases; Histiocytoma; Neoplasms, Fibrous Tissue; Neoplasms, Connective Tissue; Neoplasms, Connective and Soft Tissue; Herpesviridae Infections; Sarcoma; Neoplasms, Vascular Tissue; Skin Abnormalities; Congenital Abnormalities; Scleroderma, Systemic; Connective Tissue Diseases; Wounds and Injuries

Study Officials

• John S Nelson, M.D,Ph.D

  Beckman Laser Institue, University of California Irvine

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: J.S.Nelson, MD,PhD,Professor of Surgery and Biomedical Engineering

Study Record Dates

• First Submitted: October 4, 2007
• First Posted: October 8, 2007
• Study Start: June 1, 1999
• Primary Completion: June 1, 2008
• Study Completion: July 1, 2008
• Last Updated: October 20, 2022

Record last verified: 2022-10

Locations

US (1)