Key Insights

Highlights

Success Rate

79% trial completion

Published Results

68 trials with published results (28%)

Research Maturity

138 completed trials (57% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

15.4%

37 terminated out of 240 trials

Success Rate

78.9%

-7.6% vs benchmark

Late-Stage Pipeline

7%

17 trials in Phase 3/4

Results Transparency

49%

68 of 138 completed with results

Key Signals

68 with results79% success37 terminated

Data Visualizations

Phase Distribution

213Total
Not Applicable (26)
Early P 1 (5)
P 1 (88)
P 2 (77)
P 3 (14)
P 4 (3)

Trial Status

Completed138
Terminated37
Unknown24
Recruiting23
Active Not Recruiting7
Withdrawn7

Trial Success Rate

78.9%

Benchmark: 86.5%

Based on 138 completed trials

Clinical Trials (240)

Showing 20 of 20 trials
NCT06974734Phase 1Terminated

A Clinical Trial of PF-08046037 Alone or With Sasanlimab in Patients With Advanced or Metastatic Malignancies

NCT06150664Phase 1Recruiting

A Phase 1 of CTX-8371 in Patients With Advanced Malignancies

NCT06961006Phase 2RecruitingPrimary

A Clinical Study of Intismeran Autogene (V940) and Pembrolizumab (MK-3475) in People With Melanoma (V940-012/INTerpath-012)

NCT03236935Phase 1Completed

Phase Ib of L-NMMA and Pembrolizumab

NCT06985056Not ApplicableRecruitingPrimary

Reducing Symptom Burden Through Physical Exercise in Melanoma Patients

NCT04074096Phase 2Active Not RecruitingPrimary

Binimetinib Encorafenib Pembrolizumab +/- Stereotactic Radiosurgery in BRAFV600 Melanoma With Brain Metastasis

NCT06708455Phase 2Not Yet Recruiting

Phase 2b of RAPA-201 Cell Therapy in Post-PD-(L)-1 Melanoma

NCT06799533Phase 1TerminatedPrimary

A Study to Learn About the Study Medicine Called PF-08046031 in Advanced Melanoma and Other Solid Tumors

NCT07427953CompletedPrimary

Clinical and Functional Retinal Changes Associated With BRAF/MEK Inhibitor Therapy in Patients With Malignant Melanoma

NCT07436390Not ApplicableCompleted

IFN-Gamma Expression as a Predictor of Response to Immune Checkpoint Inhibitors in First-Line Metastatic Melanoma

NCT07431489Not ApplicableCompletedPrimary

Retinal Structural and Functional Changes in Patients Treated With BRAF/MEK Inhibitors

NCT05551117Phase 2Terminated

A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors

NCT03820986Phase 3CompletedPrimary

Safety and Efficacy Study of Pembrolizumab (MK-3475) Combined With Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Advance Melanoma (MK-7902-003/E7080-G000-312/LEAP-003)

NCT04913220Phase 1TerminatedPrimary

A Study of SAR444245 Combined With Cemiplimab for the Treatment of Participants With Various Advanced Skin Cancers (Pegathor Skin 201)

NCT07371663Phase 1Recruiting

An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors

NCT04889118Phase 3CompletedPrimary

Safety and Efficacy Study of Pembrolizumab (MK-3475) Combined With Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Advanced Melanoma (MK-7902-003/E7080-G000-312/LEAP-003)-China Extension Study

NCT00539591Phase 2Active Not RecruitingPrimary

Phase II Study Incorporating Pegylated Interferon In the Treatment For Children With High-Risk Melanoma

NCT04079166Phase 2Active Not RecruitingPrimary

SCIB1 and iSCIB1+ in Melanoma Patients Receiving Nivolumab With Ipilimumab or SCIB1 With Pembrolizumab (The SCOPE Study)

NCT05089370Phase 1Active Not RecruitingPrimary

Oral Decitabine/Cedazuridine (DEC-C) in Combination With Nivolumab for Patients With Mucosal Melanoma

NCT06332755Phase 1Recruiting

Study to Evaluate LB-LR1109, Administered Alone for the Treatment of Solid Tumor and in Combination With Atezolizumab for the Treatment of NSCLC

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