Key Insights

Highlights

Success Rate

78% trial completion

Published Results

69 trials with published results (29%)

Research Maturity

138 completed trials (57% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

15.8%

38 terminated out of 240 trials

Success Rate

78.4%

-8.1% vs benchmark

Late-Stage Pipeline

7%

17 trials in Phase 3/4

Results Transparency

50%

69 of 138 completed with results

Key Signals

69 with results78% success38 terminated

Data Visualizations

Phase Distribution

213Total
Not Applicable (26)
Early P 1 (5)
P 1 (88)
P 2 (77)
P 3 (14)
P 4 (3)

Trial Status

Completed138
Terminated38
Unknown24
Recruiting22
Active Not Recruiting7
Withdrawn7

Trial Success Rate

78.4%

Benchmark: 86.5%

Based on 138 completed trials

Clinical Trials (240)

Showing 20 of 20 trials
NCT01024231Phase 1CompletedPrimary

Dose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma

NCT06150664Phase 1Recruiting

A Phase 1 of CTX-8371 in Patients With Advanced Malignancies

NCT06985056Not ApplicableRecruitingPrimary

Reducing Symptom Burden Through Physical Exercise in Melanoma Patients

NCT06961006Phase 2RecruitingPrimary

A Clinical Study of Intismeran Autogene (V940) and Pembrolizumab (MK-3475) in People With Melanoma (V940-012/INTerpath-012)

NCT00539591Phase 2Active Not RecruitingPrimary

Phase II Study Incorporating Pegylated Interferon In the Treatment For Children With High-Risk Melanoma

NCT05130255Phase 1Terminated

GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2

NCT06636435Phase 1Recruiting

A Phase I, First in Human Study of CBA-1205, Anti-DLK1 Monoclonal Antibody in Patients With Advanced Solid Tumors, Hepatocellular Carcinoma (HCC), Melanoma, and Pediatric Cancer

NCT02644369Phase 2Active Not Recruiting

Study of the Effects of Pembrolizumab in Patients With Advanced Solid Tumors

NCT04074096Phase 2Active Not RecruitingPrimary

Binimetinib Encorafenib Pembrolizumab +/- Stereotactic Radiosurgery in BRAFV600 Melanoma With Brain Metastasis

NCT06974734Phase 1Terminated

A Clinical Trial of PF-08046037 Alone or With Sasanlimab in Patients With Advanced or Metastatic Malignancies

NCT03236935Phase 1Completed

Phase Ib of L-NMMA and Pembrolizumab

NCT06708455Phase 2Not Yet Recruiting

Phase 2b of RAPA-201 Cell Therapy in Post-PD-(L)-1 Melanoma

NCT06799533Phase 1TerminatedPrimary

A Study to Learn About the Study Medicine Called PF-08046031 in Advanced Melanoma and Other Solid Tumors

NCT07427953CompletedPrimary

Clinical and Functional Retinal Changes Associated With BRAF/MEK Inhibitor Therapy in Patients With Malignant Melanoma

NCT07436390Not ApplicableCompleted

IFN-Gamma Expression as a Predictor of Response to Immune Checkpoint Inhibitors in First-Line Metastatic Melanoma

NCT07431489Not ApplicableCompletedPrimary

Retinal Structural and Functional Changes in Patients Treated With BRAF/MEK Inhibitors

NCT05551117Phase 2Terminated

A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors

NCT03820986Phase 3CompletedPrimary

Safety and Efficacy Study of Pembrolizumab (MK-3475) Combined With Lenvatinib (MK-7902/E7080) as First-line Intervention in Adults With Advance Melanoma (MK-7902-003/E7080-G000-312/LEAP-003)

NCT04913220Phase 1TerminatedPrimary

A Study of SAR444245 Combined With Cemiplimab for the Treatment of Participants With Various Advanced Skin Cancers (Pegathor Skin 201)

NCT07371663Phase 1Recruiting

An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors

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