Key Insights

Highlights

Success Rate

86% trial completion

Published Results

23 trials with published results (14%)

Research Maturity

84 completed trials (52% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

8.6%

14 terminated out of 162 trials

Success Rate

85.7%

-0.8% vs benchmark

Late-Stage Pipeline

9%

14 trials in Phase 3/4

Results Transparency

27%

23 of 84 completed with results

Key Signals

23 with results86% success14 terminated

Data Visualizations

Phase Distribution

110Total
Not Applicable (52)
Early P 1 (4)
P 1 (16)
P 2 (24)
P 3 (10)
P 4 (4)

Trial Status

Completed84
Recruiting26
Unknown17
Terminated14
Withdrawn10
Not Yet Recruiting6

Trial Success Rate

85.7%

Benchmark: 86.5%

Based on 84 completed trials

Clinical Trials (162)

Showing 20 of 20 trials
NCT03222492Phase 1Completed

Brentuximab Vedotin for Systemic Sclerosis

NCT05204355CompletedPrimary

MRI for Screening and Monitoring Scleroderma ILD

NCT06847750Enrolling By InvitationPrimary

Elastography Ultrasound in Localized Scleroderma (Morphea) Study

NCT06880627Not ApplicableActive Not RecruitingPrimary

Brain Boost Program to Improve Cognitive Function in People With Systemic Sclerosis

NCT06801119Phase 1Recruiting

Efficacy and Safety of HN2301 in Autoimmune Diseases(AIDs)

NCT06328777Phase 1Recruiting

RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis

NCT05925803Phase 3Active Not Recruiting

Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)

NCT05995626Early Phase 1Completed

Hyaluronidase Via LADD Scleroderma-induced Microstomia

NCT02450396Withdrawn

Pregnancy and Medically Assisted Conception in Rare Diseases

NCT03207997Not ApplicableCompletedPrimary

MRI Quantification of Pulmonary Fibrosis in Scleroderma Patients

NCT04464434Phase 4Completed

Upfront Autologous HSCT Versus Immunosuppression in Early Diffuse Cutaneous Systemic Sclerosis

NCT05251415Recruiting

Clinico-biological Collection to Investigate the Physiopathology of Systemic Autoimmune Diseases

NCT07470151Not ApplicableRecruiting

Clinical Study of EVM18001 in the Treatment of Refractory Autoimmune Diseases

NCT04402086Recruiting

Rheumatology Patient Registry and Biorepository

NCT06843239Phase 2Recruiting

Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)

NCT06195072Phase 2Recruiting

Platform Clinical Study for Conquering Scleroderma

NCT07256418RecruitingPrimary

Transcriptomic Study of Cutaneous Fibroblasts in Scleroderma

NCT04610788CompletedPrimary

Cardiac Assessment by PV Loop in IPAH and Scleroderma PAH

NCT03276923Recruiting

Maternal Autoimmune Disease Research Alliance (MADRA) Registry

NCT04491396Not ApplicableCompletedPrimary

Yoga Adjunct for Scleroderma

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