NCT00531154

Brief Summary

The aim of this study is to investigate whether there was an association between obesity and periodontitis, tendency to caries and periapical lesions. People who have a higher body mass index produce cytokines (hormone-like proteins), that lead to systemic/chronic inflammation (like periodontitis and periapical lesions), and obesity related dietary habits could result in an increment of dental caries because both the amount and the frequency of sucrose ingestion are important factors associated with the aetiology of the oral disease.

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 17, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 18, 2007

Completed
Last Updated

September 18, 2007

Status Verified

September 1, 2007

First QC Date

September 17, 2007

Last Update Submit

September 17, 2007

Conditions

ObesityPeriodontitisCariesPeriapical Lesion

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Obese pateints who intended to go bariatric surgery.

You may not qualify if:

  • Coronary heart disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hadassah Medical Organization

Jerusalem, Israel

Location

Related Publications (4)

  • Pischon N, Heng N, Bernimoulin JP, Kleber BM, Willich SN, Pischon T. Obesity, inflammation, and periodontal disease. J Dent Res. 2007 May;86(5):400-9. doi: 10.1177/154405910708600503.

    PMID: 17452558BACKGROUND

  • Linden G, Patterson C, Evans A, Kee F. Obesity and periodontitis in 60-70-year-old men. J Clin Periodontol. 2007 Jun;34(6):461-6. doi: 10.1111/j.1600-051X.2007.01075.x. Epub 2007 Apr 2.

    PMID: 17403015BACKGROUND

  • Karjalainen S. Eating patterns, diet and dental caries. Dent Update. 2007 Jun;34(5):295-8, 300. doi: 10.12968/denu.2007.34.5.295.

    PMID: 17624146BACKGROUND

  • Heling I, Sgan-Cohen HD, Itzhaki M, Beglaibter N, Avrutis O, Gimmon Z. Dental complications following gastric restrictive bariatric surgery. Obes Surg. 2006 Sep;16(9):1131-4. doi: 10.1381/096089206778392211.

    PMID: 16989694RESULT

MeSH Terms

Conditions

ObesityPeriodontitis

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsPeriodontal DiseasesMouth DiseasesStomatognathic Diseases

Study Officials

  • Ilana Heling, Prof.

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ilana Heling, Prof.

CONTACT

0097226778344heling@cc.huji.ac.il

Study Design

Study Type
observational
Observational Model
DEFINED POPULATION
Time Perspective
OTHER
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 17, 2007

First Posted

September 18, 2007

Last Updated

September 18, 2007

Record last verified: 2007-09

Locations

IL(1)