NCT00516620

Brief Summary

The aim of this study is to see if the investigators can encourage people to eat more fruits, vegetables and whole grains and drink less pop by giving them advice about their diet, or by providing them with samples of different kinds of foods. The investigators are interested in the effect this has on reducing the risk of chronic disease. The investigators will also be investigating how certain genes affect the choices people make about the foods they eat.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
960

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started Jan 2005

Longer than P75 for phase_1

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2005

Completed
2.6 years until next milestone

First Submitted

Initial submission to the registry

August 13, 2007

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 15, 2007

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2011

Completed
Last Updated

December 9, 2015

Status Verified

December 1, 2015

Enrollment Period

6.3 years

First QC Date

August 13, 2007

Last Update Submit

December 8, 2015

Conditions

Keywords

Body Weight

Outcome Measures

Primary Outcomes (1)

  • Body Weight

    18 months

Secondary Outcomes (1)

  • Biomarkers of diet and obesity-related chronic diseases (serum lipids, homocysteine and C-reactive protein) and genotypes

    18 months

Study Arms (4)

1

ACTIVE COMPARATOR

Participants receive Health Canada's Food Guide and Physical Activity guide.

Behavioral: No further instructionBehavioral: Food DeliveryBehavioral: Fruits (F), vegetables (V), and whole grain (WG) counselingBehavioral: Counseling to reduce soft drink intake.Behavioral: Food Delivery & F, V & WG counseling.Behavioral: Food delivery & soft drink counselingBehavioral: F, V, WG & soft drink counselingBehavioral: Food delivery and F,V, WG & soft drink counseling

2

ACTIVE COMPARATOR

Participants receive a weekly sample food basket for 6 months consisting of fruits, vegetables, whole grains, and vegetable protein products.

Behavioral: Food DeliveryBehavioral: Food Delivery & F, V & WG counseling.Behavioral: Food delivery & soft drink counselingBehavioral: Food delivery and F,V, WG & soft drink counseling

3

ACTIVE COMPARATOR

Participants receive intensive dietary counseling for 6 months to increase intake of fruits, vegetables, whole grains, and vegetable protein products.

Behavioral: Fruits (F), vegetables (V), and whole grain (WG) counselingBehavioral: Food Delivery & F, V & WG counseling.Behavioral: F, V, WG & soft drink counselingBehavioral: Food delivery and F,V, WG & soft drink counseling

4

ACTIVE COMPARATOR

Participants receive intensive dietary counseling for 6 months to decrease intake of sweetened soft drink.

Behavioral: Counseling to reduce soft drink intake.Behavioral: Food delivery & soft drink counselingBehavioral: F, V, WG & soft drink counselingBehavioral: Food delivery and F,V, WG & soft drink counseling

Interventions

Participants receive Health Canada's Food Guide and Physical Activity Guide and no other intervention for the 6 months of the intervention period.

Also known as: Control
1
Food DeliveryBEHAVIORAL

Participants receive Canada's Food Guide and Physical Activity guide, in addition to a a weekly sample food basket for 6 months consisting of fruits, vegetables, whole grains, and vegetable protein products.

12

Participants receive Canada's Food Guide and Physical Activity guide, and intensive dietary counseling for 6 months to increase intake of fruits, vegetables, whole grains, and vegetable protein products. The counselling frequency will be weekly intervals for the first month, and then monthly sessions for the second to sixth months.

Also known as: Fruit, Vegetable and Whole Grain Counseling
13

Participants receive Health Canada's Food Guide and Physical Activity guide, and intensive dietary counseling for 6 months to decrease intake of sweetened soft drink. The counselling frequency will be weekly intervals for the first month, and then monthly sessions for the second to sixth months.

Also known as: Sweetened Soft Drink Counseling
14

Participants receive Health Canada's Food Guide and Physical Activity guide, a weekly sample food basket for 6 months consisting of fruits, vegetables, whole grains, and vegetable protein products, and intensive dietary counseling to increase intake of fruits, vegetables, whole grains, and vegetable protein products. The counselling frequency will be weekly intervals for the first month, and then monthly sessions for the second to sixth months.

Also known as: Food Delivery, Fruit, Vegetable and Whole Grain Counseling
123

Participants receive Health Canada's Food Guide and Physical Activity guide, a weekly sample food basket for 6 months consisting of fruits, vegetables, whole grains, and vegetable protein products, and intensive dietary counseling for 6 months to decrease intake of sweetened soft drink. The counselling frequency will be weekly intervals for the first month, and then monthly sessions for the second to sixth months.

Also known as: Food Delivery, and Sweetened Soft Drink Counseling
124

Participants receive Health Canada's Food Guide and Physical Activity guide, and intensive dietary counseling for 6 months to increase intake of fruits, vegetables, whole grains, and vegetable protein products, and also to decrease intake of sweetened soft drink. The counseling frequency will be weekly intervals for the first month, and then monthly sessions for the second to sixth months.

Also known as: Fruit, Vegetable, Whole Grain, Sweetened Soft Drink Counseling
134

Participants receive Health Canada's Food Guide and Physical Activity guide, receive a weekly sample food basket for 6 months consisting of fruits, vegetables, whole grains, and vegetable protein products, and intensive dietary counseling for 6 months to increase intake of fruits, vegetables, whole grains, and vegetable protein products, and also to decrease intake of sweetened soft drink. The counselling frequency will be weekly intervals for the first month, and then monthly sessions for the second to sixth months.

Also known as: Food Delivery, Fruit, Vegetable, Whole Grain, and Sweetened Soft Drink Counseling
1234

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • residents of households within the City of Toronto 416 calling area
  • respond to advertisements in newspaper, on radio, and from flyers
  • Eligible households will include at least one willing adult 18 years or older; able to communicate in English, at least one adult with BMI \>/= 25
  • Pregnant and breastfeeding mothers who fit the criteria above are eligible to join the study 6 months post-partum or 6 months after the cessation of breastfeeding

You may not qualify if:

  • Residing outside of the 416 area code
  • under 18 years of age
  • actively following a special diet or weight-loss program
  • major cardiovascular event in the previous 6 months
  • recently (past 6 months) started blood pressure medication
  • diabetes, liver disease, renal failure, cancer (or a history of malignancy), inflammatory bowel disease, individuals with acute or chronic infections, either bacterial or viral, or individuals suffering from chronic inflammatory diseases, irritable bowel syndrome, peanut or nut allergy, major surgery in the previous 6 months
  • blood pressure greater than 145/95 on repeated measurements will be excluded

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Toronto

Toronto, Ontario, M5S 3E2, Canada

Location

Related Publications (3)

  • Jamnik J, Villa CR, Dhir SB, Jenkins DJA, El-Sohemy A. Prevalence of positive coeliac disease serology and HLA risk genotypes in a multiethnic population of adults in Canada: a cross-sectional study. BMJ Open. 2017 Oct 6;7(10):e017678. doi: 10.1136/bmjopen-2017-017678.

  • Wang J, Jamnik J, Garcia-Bailo B, Nielsen DE, Jenkins DJA, El-Sohemy A. ABO Genotype Does Not Modify the Association between the "Blood-Type" Diet and Biomarkers of Cardiometabolic Disease in Overweight Adults. J Nutr. 2018 Apr 1;148(4):518-525. doi: 10.1093/jn/nxx074.

  • Jenkins DJA, Boucher BA, Ashbury FD, Sloan M, Brown P, El-Sohemy A, Hanley AJ, Willett W, Paquette M, de Souza RJ, Ireland C, Kwan N, Jenkins A, Pichika SC, Kreiger N. Effect of Current Dietary Recommendations on Weight Loss and Cardiovascular Risk Factors. J Am Coll Cardiol. 2017 Mar 7;69(9):1103-1112. doi: 10.1016/j.jacc.2016.10.089.

MeSH Terms

Conditions

Heart DiseasesDiabetes MellitusHypertensionBody Weight

Interventions

FruitVegetablesWhole GrainsCounseling

Condition Hierarchy (Ancestors)

Cardiovascular DiseasesGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesVascular DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

FoodDiet, Food, and NutritionPhysiological PhenomenaFood and BeveragesEdible GrainCrops, AgriculturalSeedsMental Health ServicesBehavioral Disciplines and ActivitiesCommunity Health ServicesHealth ServicesHealth Care Facilities Workforce and Services

Study Officials

  • Daivd JA Jenkins, MD, PhD

    University of Toronto, St. Michael's Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

August 13, 2007

First Posted

August 15, 2007

Study Start

January 1, 2005

Primary Completion

May 1, 2011

Study Completion

May 1, 2011

Last Updated

December 9, 2015

Record last verified: 2015-12

Locations