Occurrence of Pneumocystis Pneumonia in HIV-Infected Patients and the Interference of the HAART

NCT00516581 | Completed DMC

• 2 other identifiers: upeclin/HC/FMB-Unesp-13PCP UnespFMB 2003
• Study Type: observational
• Target: 376
• Locations: 1 country
• Sites: 1

Brief Summary

From the beginning of the AIDS epidemic, pulmonary pneumocystosis (PCP) has been distinguished as one of the most frequent opportunistic diseases with high morbid-mortality. As from 1996, the advent of the highly active antiretroviral therapy (HAART) has changed the characteristics of such epidemic by reducing its related diseases and, as a result, AIDS-related mortality. With the purpose to estimate PCP occurrence and HAART interference, 376 HIV-infected or AIDS patients were studied from January 1992 to December 2002.

Conditions

HIV

Keywords

Pneumocystis Pneumonia; Acquired Immune Deficiency Syndrome; Highly Active Antiretroviral Therapy; Treatment Experienced; Treatment Naive

Study Arms (2)

no HAART

Patients that no received HAART

with HAART

Patients that received HAART

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

376 HIV-infected or AIDS patients were studied from January 1992 to December 2002

You may qualify if:

• HIV infection

You may not qualify if:

• No HIV infection

Sponsors & Collaborators

• UPECLIN HC FM Botucatu Unesp: lead

Study Sites (1)

Faculdade de Medicina de Botucatu - Unesp

Botucatu, São Paulo, 18618970, Brazil

Location

MeSH Terms

Conditions

Pneumonia, Pneumocystis; Acquired Immunodeficiency Syndrome

Condition Hierarchy (Ancestors)

Lung Diseases, Fungal; Mycoses; Bacterial Infections and Mycoses; Infections; Pneumocystis Infections; Respiratory Tract Infections; Pneumonia; Lung Diseases; Respiratory Tract Diseases; HIV Infections; Blood-Borne Infections; Communicable Diseases; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Slow Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases

Study Officials

• Alexandre N Barbosa, MD, MSc

  UPECLIN HC FM Botucatu Unesp

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: August 14, 2007
• First Posted: August 15, 2007
• Study Start: February 1, 2003
• Study Completion: February 1, 2005
• Last Updated: September 5, 2008

Record last verified: 2008-09

Locations

BR (1)