Lung Disease Collection (Qatar): Evaluation of the Lungs of Individuals With Lung Disease

NCT00504738 | Completed DMC

• 2 other identifiers: 0604008489HMC RC392/2006
• Study Type: observational
• Target: 75
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this protocol is to obtain biologic samples from the blood and lungs from patients with lung diseases in order to study the causes and indications of these disorders, learn how these lung disease manifest and progress, and how the lung disease can be treated.

Conditions

Lung Disease; Chronic Obstructive Pulmonary Disease (COPD); Asthma

Keywords

lung disease; chronic obstructive pulmonary disease (COPD); asthma; smokers; non-smokers

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Recruitment will be from the patients of the Hamad Medical Corporation and others as relevant. The source of potential subjects will be the population of potential subjects with lung disease, as defined by the elegibility criteria, in Qatar. Accrual will be random with no bias as to gender or racial/ethnic group.

You may not qualify if:

• Must provide informed consent
• Males and females, age 18 years and older
• Evidence of lung disease by at least one of the following:
• symptoms consistent with pulmonary disease;
• chest X-rays and/or chest CT consistent with lung disease;
• pulmonary function tests consistent with lung disease;
• lung biopsy consistent with lung disease;
• family history of lung disease;
• diseases of organs with known association with lung disease; and
• individuals suspected of having lung disease based on history and/or physical examination
• Undergoing fiberoptic bronchoscopy as dictated by their standard clinical care
• Patient refuses consent.
• Patients enrolled in Part A of the protocol will not undergo screening procedures/tests. These patients are undergoing a fiberoptic bronchoscopy as dictated by their standard clinical care and additional samples will be taken for research purposes.

Sponsors & Collaborators

• Weill Medical College of Cornell University: lead
• Weill Cornell Medical College in Qatar: collaborator
• Hamad Medical Corporation: collaborator

Study Sites (1)

Hamad Medical Corporation

Doha, Qatar

Location

Biospecimen

Retention: SAMPLES WITH DNA

The purpose of this protocol is to obtain biologic samples from the blood and lungs from patients with lung diseases in order to study the causes and indications of these disorders, learn how these lung disease manifest and progress, and how the lung disease can be treated.

MeSH Terms

Conditions

Lung Diseases; Pulmonary Disease, Chronic Obstructive; Asthma

Condition Hierarchy (Ancestors)

Respiratory Tract Diseases; Lung Diseases, Obstructive; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Bronchial Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Study Officials

• Ronald G. Crystal, MD

  Weill Cornell Medical College, New York and Qatar

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 19, 2007
• First Posted: July 20, 2007
• Study Start: April 1, 2006
• Study Completion: April 1, 2007
• Last Updated: April 21, 2015

Record last verified: 2015-04

Locations

QA (1)