NCT00504361|Completed
Blood Collection From Individuals With Lung Disease for Genetic Studies (Qatar)
Q-BC
Collection of Blood for Gene Expression Study in Individuals With Chronic Lung Diseases (Qatar)
Loading search results
Q-BC
Collection of Blood for Gene Expression Study in Individuals With Chronic Lung Diseases (Qatar)
Sponsor study identifier
Secondary identifiers
OTHER · Hamad Medical Corporation
observational
600
1 country
1
Study Start
May 2006
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
May 2012
Actual (reported)Study Completion
May 2012
Actual (reported)This is a research study where researchers are collecting blood to evaluate the genetic characteristics of individuals with chronic lung diseases, including asthma, COPD (chronic obstructive pulmonary disease), interstitial lung disease, cystic fibrosis, and lung cancer. The investigators hope to be able to identify an association between a genetic make-up in the blood samples and the risks of developing a particular lung disease, or severity of a lung disease. The findings of this study might be important to develop future preventative methods and potential treatments for the management of lung disease.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 2012
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
May 2006
Date type not reportedThis date has not been verified as actual or estimated.
July 19, 2007
Actual (reported)July 20, 2007
Actual (reported)May 2012
Actual (reported)May 2012
Actual (reported)Genomic DNA will be extracted, and genome wide SNP analysis and promoter sequences for genes will be obtained.
5 years
Individuals with at least one of the following: (1) symptoms consistent with pulmonary disease; (2) chest X-ray consistent with lung disease; (3) pulmonary function tests consistent with lung disease; (4) lung biopsy consistent with lung disease; (5) family history of lung disease; (6) patients with diseases of organs with known association with lung disease; and (7) individuals suspected of history of lung diseased based on history and/or physical examination
Individuals without a history of lung disease.
Individuals visiting the Medicine Department at the Hamad Medical Corporation, Qatar for standard clinical care will be recruited. Controls will be obtained from volunteers without a history of lung disease. Family members of patients may be asked to participate in the study.
Hamad Medical Corporation
Doha, Qatar
This protocol is designed to collect a small amount of blood for extraction of DNA (genetic material) for the study of the genetic basis of lung disease. Genomic DNA will be extracted, and genome wide SNP analysis and promoter sequences for genes will be obtained. The goal is to find single nucleotide polymorphims (SNP), small changes in single genes that affect disease risk, to see if they correlate with lung disease.
Ronald G Crystal, MD
Weill Cornell Medical College, NY and Qatar
600 participants (actual enrollment reported by the registry).
First Submitted
July 19, 2007
First Posted
July 20, 2007
Study Start
May 2006
Date type not reportedThis date has not been verified as actual or estimated.
The Natural History of Small Airways Physiology in Diseased and Healthy States
Contact the study team to confirm eligibility.
Primary Completion
May 2012
Actual (reported)Study Completion
May 2012
Actual (reported)Last Updated
May 2, 2016
Record last verified: 2016-04
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: