NCT00491647

Brief Summary

Background: Literature has documented that children with attention-deficit/ hyperactivity disorder (ADHD) have difficulties in time management by manifesting with difficulties making plans, organizing tasks and activities, and awaiting their turns. However, the studies regarding time perception have been few as compared to those of neuropsychological measures and there is no information about this topic in Chinese population. In view of this, we will conduct a study to investigate the clinical and treatment aspects of time perception among children and adolescent with ADHD. Specific Aims:

  1. 1.to examine the developmental and gender effect on the performance in time perception;
  2. 2.to explore the deficit in time estimation, time discrimination, and time reproduction in children and adolescents with ADHD as compared to normal controls;
  3. 3.to identify the association between ADHD symptoms and performance in time perception tasks; and
  4. 4.to investigate the efficacy of MPH on the time perception measures among children and adolescents with ADHD; Subjects and Methods: This protocol consists of two studies. First, we will recruit 100 patients with DSM-IV ADHD, aged 9 to 16 years, and 100 school controls. They and their parents will receive K-SADS-E interviews. All of them will have complete assessments of time estimation, time discrimination, and time reproduction. Their parents also report on SNAP-IV and CPRS-R:S. The 2nd assessments will be performed 3 months later after the subjects received treatment at outpatients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
258

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2006

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2006

Completed
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2007

Completed
22 days until next milestone

First Submitted

Initial submission to the registry

June 23, 2007

Completed
3 days until next milestone

First Posted

Study publicly available on registry

June 26, 2007

Completed
Last Updated

November 14, 2012

Status Verified

September 1, 2008

First QC Date

June 23, 2007

Last Update Submit

November 12, 2012

Conditions

Keywords

ADHD, time perception, treatments

Eligibility Criteria

Age9 Years - 16 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Children with and without ADHD

You may qualify if:

  • Case group:
  • DSM-IV ADHD,
  • aged 9 to 16 years,
  • IQ \> 80,
  • Subjects and Parents consent to the study.
  • Control:
  • No ADHD,
  • aged 9 to 16 years,
  • IQ \> 80,
  • Subjects and Parents consent to the study.

You may not qualify if:

  • A history of brain injury or epilepsy,
  • visual/auditory deficit or were diagnosed as having motor disorder,
  • obsessive-compulsive disorder,
  • mental retardation, and depression.
  • In order to recruit a population of pure ADHD (without other psychiatric comorbidities), children who are comorbid with oppositional defiant disorder (ODD) or conduct disorder (CD) were excluded, though the concurrence of ODD/CD and ADHD

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan Univeristy Hospital

Taipei, 10002, Taiwan

Location

Related Publications (1)

  • Hwang SL, Gau SS, Hsu WY, Wu YY. Deficits in interval timing measured by the dual-task paradigm among children and adolescents with attention-deficit/hyperactivity disorder. J Child Psychol Psychiatry. 2010 Mar;51(3):223-32. doi: 10.1111/j.1469-7610.2009.02163.x. Epub 2009 Sep 15.

MeSH Terms

Conditions

Attention Deficit Disorder with Hyperactivity

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior DisordersNeurodevelopmental DisordersMental Disorders

Study Officials

  • Susan Shur-Fen Gau, MD, PhD

    National Taiwan University Hospital & College of Medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 23, 2007

First Posted

June 26, 2007

Study Start

May 1, 2006

Study Completion

June 1, 2007

Last Updated

November 14, 2012

Record last verified: 2008-09

Locations