NCT00479804

Brief Summary

The cardiac output (CO) is an important parameter in the diagnosis and therapy of cardiac diseases. The current standard methods for the determination of the CO, however, are either invasive (e.g. right heart catheterization) or technically expendable and expensive (magnetic resonance tomography, MRT). The traditional non-invasive methods of determining the CO by rebreathing of carbon dioxide are easily carried out but suffer from methodical inaccuracies. Therefore the aim of the study at hand was to evaluate a new method for determining the CO by means of the inert gas rebreathing method.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
311

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Aug 2006

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2006

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

May 25, 2007

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 28, 2007

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2007

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2007

Completed
Last Updated

June 5, 2008

Status Verified

June 1, 2008

Enrollment Period

1.3 years

First QC Date

May 25, 2007

Last Update Submit

June 4, 2008

Conditions

Cardiac Diseases

Keywords

indication for CMR

Interventions

inertgas rebreathingDEVICE

determination of cardiac output by inertgas rebreathing

spirometryDEVICE

spirometry for testing the ventilatory function

cardiac magnetic resonance imaging (CMR)DEVICE

CMR examination which delivers the hemodynamic reference parameters

Eligibility Criteria

Age14 Years - 90 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Study Population

Consecutive patients with indication for CMR

You may qualify if:

  • Indication for CMR
  • Ability of following instructions for rebreathing test

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

1st Department of Medicine, University Hospital Mannheim

Mannheim, Baden-Wurttemberg, 68167, Germany

Location

MeSH Terms

Conditions

Heart Diseases

Interventions

Spirometry

Condition Hierarchy (Ancestors)

Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Respiratory Function TestsDiagnostic Techniques, Respiratory SystemDiagnostic Techniques and ProceduresDiagnosis

Study Officials

  • Joachim Saur, Dr.

    1st Department of Medicine

    STUDY DIRECTOR

  • Jens Kaden, Dr.

    1st Deparment of Medicine

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 25, 2007

First Posted

May 28, 2007

Study Start

August 1, 2006

Primary Completion

December 1, 2007

Study Completion

December 1, 2007

Last Updated

June 5, 2008

Record last verified: 2008-06

Locations

DE(1)