NCT00476684

Brief Summary

There is conflicting evidence on whether radio-frequency neurotomy of the medial branch has a significant effect on pain in patients with chronic unilateral facet joint neck and back pain. We will evaluate radiofrequency treatment on medial-branch of the ramus dorsalis as an effective pain treatment for patients with chronic pain originated from facet-joints in cervical and lumbar columna.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2004

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2004

Completed
2.8 years until next milestone

First Submitted

Initial submission to the registry

May 21, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 22, 2007

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2010

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2011

Completed
Last Updated

August 22, 2017

Status Verified

August 1, 2017

Enrollment Period

5.8 years

First QC Date

May 21, 2007

Last Update Submit

August 17, 2017

Conditions

Keywords

radiofrequency

Outcome Measures

Primary Outcomes (1)

  • reduction in self-reported pain intensity

    Numerig rating scale 1 to 10

    up to 1 year

Study Arms (2)

radiofrequency neurotomy

EXPERIMENTAL

Radiofrequency-neurotomy of the medial branch at 80 degr. C for 70 seconds, after diagnostic blocks

Procedure: radiofrequency treatment

sham controls

SHAM COMPARATOR

Radiofrequency-neurotomy of the medial branch at 37 degr. C needle temperature for 70 seconds, after diagnostic blocks

Procedure: sham neurotomy

Interventions

Radiofrequency-neurotomy of the medial branch at 80 degr. C needle temperature for 70 seconds, after diagnostic blocks

radiofrequency neurotomy

Radiofrequency-neurotomy of the medial branch at 37 degr. C needle temperature for 70 seconds, after diagnostic blocks

sham controls

Eligibility Criteria

Age20 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • one-sided neck and low back chronic pain
  • pain durability of at least 1 year

You may not qualify if:

  • other somatic or psychiatric disorders
  • pregnancy
  • stated co-morbidity
  • anaesthetics intolerance
  • no effect of diagnostic blockades (one or two)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pain Clinic, University Hospital of Trondheim

Trondheim, 7006, Norway

Location

MeSH Terms

Conditions

Neck PainLow Back Pain

Interventions

Pulsed Radiofrequency Treatment

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsBack Pain

Intervention Hierarchy (Ancestors)

Electric Stimulation TherapyTherapeuticsPhysical Therapy ModalitiesRadiofrequency TherapyRehabilitation

Study Officials

  • Petter C. Borchgrevink, prof. PhD MD

    Norwegian University of Science and Technology

    PRINCIPAL INVESTIGATOR
  • Tarjei Rygnestad, Prof. PhD MD

    Norwegian University of Science and Technology

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 21, 2007

First Posted

May 22, 2007

Study Start

August 1, 2004

Primary Completion

May 1, 2010

Study Completion

May 1, 2011

Last Updated

August 22, 2017

Record last verified: 2017-08

Locations