NCT00469339

Brief Summary

This study will examine what methods work best for encouraging Mexican-American family members to talk about their risk for diabetes, heart disease, breast cancer and colon cancer. Within the Mexican-American community, the family culture provides an important setting in which individuals interpret and share their health information and formulate strategies to engage in health-promoting behaviors. The information from the study will be used to design risk communication approaches for Mexican-American households. Members of households with at least three adults 18 to 70 years of age who are part of the existing Mexican-American households recruited by the University of Texas M.D. Anderson Cancer Center may be eligible for this study. Participants are interviewed about their medical history, family history of disease, health behaviors, beliefs about disease and disease risk, experiences living in the United States, and relationships with family members and close friends. They are then provided information about their family risk for diabetes, heart disease, breast cancer and colon cancer, based on the information they provided in the interview. Two additional interviews are conducted over the telephone that include questions about how the participants communicate with family members about their risk and health behaviors.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
498

participants targeted

Target at P75+ for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 27, 2007

Completed
6 days until next milestone

First Submitted

Initial submission to the registry

May 3, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 4, 2007

Completed
Last Updated

May 1, 2026

Status Verified

July 8, 2025

First QC Date

May 3, 2007

Last Update Submit

April 30, 2026

Conditions

Keywords

Breast CancerDiabetesColon CancerCardiovascular DiseaseNatural History

Outcome Measures

Primary Outcomes (4)

  • Understand how culture and the familial social system facilitate or impede communications regarding family health history and risk for disease, and the development of strategies to adopt health promoting behaviors.

    Understand how culture and the familial social system facilitate or impede communications regarding family health history and risk for disease, and the development of strategies to adopt health promoting behaviors.

    one survey and two telephone interviews

  • Investigate whether the type of personalized risk feedback (predisposing or predisposing plus enabling) affects family members beliefs about the causes and controllability of disease onset and perceived risk for disease.

    Investigate whether the type of personalized risk feedback (predisposing or predisposing plus enabling) affects family members beliefs about the causes and controllability of disease onset and perceived risk for disease.

    one survey and two telephone interviews

  • Investigate whether shared perceptions of risk and beliefs about disease mediates the relationship between communications about family risk and the development of cooperative strategies to adopt health promoting behaviors within the family.

    Investigate whether shared perceptions of risk and beliefs about disease mediates the relationship between communications about family risk and the development of cooperative strategies to adopt health promoting behaviors within the family.

    one survey and two telephone interviews

  • Examine whether a family-centered feedback approach, as compared to an individual-focused approach, encourages communications regarding family risk and the development of strategies to adopt health promoting behaviors within the household.

    Examine whether a family-centered feedback approach, as compared to an individual-focused approach, encourages communications regarding family risk and the development of strategies to adopt health promoting behaviors within the household.

    one survey and two telephone interviews

Study Arms (1)

cohort of Mexican-American households

cohort of Mexican-American households

Behavioral: Family Health History

Interventions

cohort of Mexican-American households

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Mexican-American households@@@

You may qualify if:

  • Member household of existing population-based cohort of Mexican-American households recruited by the Department of Epidemiology at UTMDACC. The existing population based cohort consists of self-identified Mexican-Americans living in predominantly Mexican-American neighborhoods in the Houston area. All individuals in the cohort are 18 years of age or older and had to be able to complete a personal interview.
  • Household includes at least three adults (18 to 70 years of age) who are willing to participate in the study, where at least two of the household participants are related biologically and represent differing generations, and additionally in which one household participant is a spouse or partner of another household participant.
  • Ability for each participating household member to complete one in-home survey instrument via computerized assessment tool or personal interview and to complete two telephone interviews.
  • Ability of all household participants to speak either English or Spanish.

You may not qualify if:

  • More than two household members are unable to complete the baseline questionnaire using a computerized assessment tool.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

MD Anderson Cancer Center

Houston, Texas, 77030-4096, United States

Location

Related Publications (4)

  • Glass TA, McAtee MJ. Behavioral science at the crossroads in public health: extending horizons, envisioning the future. Soc Sci Med. 2006 Apr;62(7):1650-71. doi: 10.1016/j.socscimed.2005.08.044. Epub 2005 Sep 29.

    PMID: 16198467BACKGROUND
  • Green LW. Public health asks of systems science: to advance our evidence-based practice, can you help us get more practice-based evidence? Am J Public Health. 2006 Mar;96(3):406-9. doi: 10.2105/AJPH.2005.066035. Epub 2006 Jan 31.

    PMID: 16449580BACKGROUND
  • Susser M. The tribulations of trials--intervention in communities. Am J Public Health. 1995 Feb;85(2):156-8. doi: 10.2105/ajph.85.2.156. No abstract available.

    PMID: 7856769BACKGROUND
  • Lin J, Marcum CS, Wilkinson AV, Koehly LM. Developing Shared Appraisals of Diabetes Risk Through Family Health History Feedback: The Case of Mexican-Heritage Families. Ann Behav Med. 2018 Feb 17;52(3):262-271. doi: 10.1093/abm/kax037.

MeSH Terms

Conditions

Breast NeoplasmsDiabetes MellitusColonic NeoplasmsCardiovascular Diseases

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue DiseasesGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesColorectal NeoplasmsIntestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal Diseases

Study Officials

  • Laura M Koehly, Ph.D.

    National Human Genome Research Institute (NHGRI)

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
NIH
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 3, 2007

First Posted

May 4, 2007

Study Start

April 27, 2007

Last Updated

May 1, 2026

Record last verified: 2025-07-08

Locations