Breast Cancers: Risk Factors Among Mexican Women in Mexico, Mexican-American and African-American Women in the U.S.
Comparative Study of Breast Cancers and Their Risk Factors Among Mexican Women in Mexico, Mexican-American and African-American Women in the U.S.
2 other identifiers
observational
938
2 countries
7
Brief Summary
The goal of this epidemiologic research study is to find out if various risk factors and certain markers (substances that help identify the presence of cancer) that help predict increased occurrence and prognosis (outcome of disease) of breast cancer differ among Mexican, Mexican-American, and African-American women.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2007
Longer than P75 for all trials
7 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2007
CompletedFirst Submitted
Initial submission to the registry
February 4, 2009
CompletedFirst Posted
Study publicly available on registry
February 5, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 10, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
May 10, 2021
CompletedMay 14, 2021
May 1, 2021
14.4 years
February 4, 2009
May 12, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Categorical Response Variables
5 years
Secondary Outcomes (1)
Expression of a breast tumor phenotype marker (expressed versus not expressed)
5 Years
Study Arms (3)
Mexican Women from Mexico
Mexican-American Women in U.S.
African-American Women in U.S.
Interventions
Interview and survey during visit or by phone, 30 - 40 minutes.
Eligibility Criteria
Woman, 18 years or older, of Mexican descent (Mexican or Mexican-American) or an African-American woman, and have invasive breast cancer during past 12 months.
You may qualify if:
- All women of Mexican and African descent ages 18 years or older.
- Diagnosis of invasive breast cancer (histologically confirmed invasive adenocarcinoma, including ductal, lobular, medullary, tubular and mucinous cellular patterns) within the past 24 months.
- Willing to complete a questionnaire.
- Consent to tissue acquisition (remaining after surgery or preoperative core needle biopsy).
You may not qualify if:
- Male gender
- Inadequate tissue obtained for the four main clinical markers (ER, PR, Her-2/neu and Ki67).
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- M.D. Anderson Cancer Centerlead
- National Cancer Institute (NCI)collaborator
Study Sites (7)
Arizona Cancer Center
Tucson, Arizona, 85724-5024, United States
LBJ Hospital
Houston, Texas, 77030, United States
University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
The Rose Diagnostic Center
Houston, Texas, 77034, United States
University of Sonora
Hermosillo, Sonora, Mexico
Instituto Tecnologico
Ciudad Obregón, Mexico
University of Guadalajara
Guadalajara, Mexico
Related Links
Biospecimen
One-time blood draw (about 3 tablespoons). If blood cannot be drawn or not enough blood can be drawn, a saliva sample will be taken.
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Abenaa M. Brewster, MD, MHS, BS
M.D. Anderson Cancer Center
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 4, 2009
First Posted
February 5, 2009
Study Start
January 1, 2007
Primary Completion
May 10, 2021
Study Completion
May 10, 2021
Last Updated
May 14, 2021
Record last verified: 2021-05