Plasmodium Resistance in A. Gambiae
Genetic Association Mapping of Malaria Resistance in Anopheles Gambiae
1 other identifier
observational
40
1 country
1
Brief Summary
The purpose of this study is to find new ways to control malaria by looking at mosquitoes infected with the disease. Knowledge of the genetics that affect the spread of malaria by mosquitoes will help in developing control strategies. A small amount of blood from infected humans will be used to infect the mosquitoes. No contact will occur between the human subject and the mosquito. Study participants will be divided into 2 groups of 20, for a total of 40 children, ages 5-10, in Burkina Faso, West Africa. Each subject will be screened by finger-prick once per month, from June through October, until they reach a maximum age of 10. Two positive subjects of the 40 screened will be asked to donate about 1 teaspoon of blood, which will be used to feed and infect the mosquitoes. Study participants will be involved in study related procedures for a maximum of 5 years.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 26, 2007
CompletedFirst Posted
Study publicly available on registry
April 27, 2007
CompletedStudy Start
First participant enrolled
June 1, 2007
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 30, 2012
CompletedJanuary 31, 2019
May 1, 2012
4.9 years
April 26, 2007
January 30, 2019
Conditions
Keywords
Eligibility Criteria
You may qualify if:
- Age 5-10 years old
- No major diagnosable health problems (compared to local population)
- Willing to participate in the study
- Identified as having a malaria infection by blood film examination
You may not qualify if:
- Specific major diagnosable health problems
- Not willing to participate in the study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Centre National de Recherche et de Formation sur le Paludisme
West Africa, Burkina Faso
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- NIH
Study Record Dates
First Submitted
April 26, 2007
First Posted
April 27, 2007
Study Start
June 1, 2007
Primary Completion
April 30, 2012
Last Updated
January 31, 2019
Record last verified: 2012-05