Exercise and Activities for Independent Living With Mild Cognitive Impairment (MCI)

NCT00446394 | Completed DMC

• 4 other identifiers: 30692-J2R01AG014777IA010006-3067-C
• Study Type: interventional
• Target: 181
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this project is to evaluate an exercise and health promotion program for older adults with mild memory loss. The study will investigate the efficacy of a memory-enhanced exercise and health promotion program to determine whether it is more effective than a social walking program in delaying further memory decline, improving mood and physical function, and enhancing quality of life.

Conditions

Mild Cognitive Impairment; Dementia

Keywords

cognition disorder; functional ability; psychomotor function; psychopathology; quality of life

Outcome Measures

Primary Outcomes (1)

• Changes in cognitive status

  baseline, 3, 6, 12, 18, 24, 30, and 36 months

Secondary Outcomes (1)

• Changes in health, affective, and functional status

  baseline, 3, 6, 12, 18, 24, 30, and 36 months

Study Arms (2)

1

EXPERIMENTAL

Behavioral: Resources and Activities for Life Long Independence (RALLI)

2

ACTIVE COMPARATOR

Behavioral: Social Walking program (SW)

Interventions

Resources and Activities for Life Long Independence (RALLI) BEHAVIORAL

Strengthening exercises, encouragement to walk daily, pedometer reading, health promotion information for 1.5 hours weekly for 9 weeks

1

Social Walking program (SW) BEHAVIORAL

Group support for walking, pedometer reading, 1 hour weekly for 9 weeks

2

Eligibility Criteria

• Age: 70 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• Mild Cognitive Impairment defined as
• \- Memory complaint
• \- Objective memory impairment for age and education
• \- Largely intact general cognitive function
• \- Essentially preserved activities of daily living
• \- Not already diagnosed with dementia
• Insufficient physical activity defined as less than 150 minutes per week of moderate intensity physical activity
• Not currently in an exercise program similar to the study program

You may not qualify if:

• Not ambulatory
• Expected to move from the study geographic area during the study period
• Have a known terminal illness
• Actively suicidal, hallucinating, or delusional
• Hospitalized for a psychiatric disorder in the 12 months before baseline
• Uncontrolled chronic conditions, e.g. uncontrolled hypertension, unstable angina, uncontrolled blood glucose
• Blind or deaf

Sponsors & Collaborators

• University of Washington: lead

Study Sites (1)

Northwest Research Group on Aging, Department of Psychosocial and Community Health, University of Washington School of Nursing

Seattle, Washington, 98105, United States

Location

MeSH Terms

Conditions

Cognitive Dysfunction; Dementia; Cognition Disorders

Interventions

Health Resources; Exercise

Condition Hierarchy (Ancestors)

Neurocognitive Disorders; Mental Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Intervention Hierarchy (Ancestors)

Health Planning; Health Care Economics and Organizations; Delivery of Health Care; Health Care Quality, Access, and Evaluation; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Linda Teri, PhD

  University of Washington School of Nursing

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: March 8, 2007
• First Posted: March 12, 2007
• Study Start: June 1, 2007
• Primary Completion: October 1, 2012
• Study Completion: October 1, 2012
• Last Updated: October 19, 2012

Record last verified: 2012-10

Locations

US (1)