NCT00439114

Brief Summary

This study is planned to compare the results of ultrasonic and Orbscan pachymetry in corneal haze not related to surgery. Corneal haze is graded with slit-lamp by a single examiner. Ultrasonic and Orbscan II pachymetry measurements are obtained. Paired t and Kruskal-Wallis tests are used to evaluate the difference between ultrasonic and Orbscan pachymetry measurements. Correlation of the two methods and haze grade is determined with Kendall's tau-b correlation analysis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jul 2005

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2005

Completed
11 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2006

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

February 21, 2007

Completed
2 days until next milestone

First Posted

Study publicly available on registry

February 23, 2007

Completed
Last Updated

February 23, 2007

Status Verified

February 1, 2007

First QC Date

February 21, 2007

Last Update Submit

February 21, 2007

Conditions

Corneal Opacity

Keywords

Corneal topography, corneal opacity, keratitis, trachoma

Eligibility Criteria

Age18 Years - 71 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with significant corneal haze on slit-lamp are included in the study group. 50 eyes of 50 age-matched patients with normal eye and clear cornea are included in the control group. Only one eye of each subject is included.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Baskent University, Faculty of Medicine, Adana Hospital

Adana, 01250, Turkey (Türkiye)

Location

Related Publications (3)

  • Boscia F, La Tegola MG, Alessio G, Sborgia C. Accuracy of Orbscan optical pachymetry in corneas with haze. J Cataract Refract Surg. 2002 Feb;28(2):253-8. doi: 10.1016/s0886-3350(01)01162-2.

    PMID: 11821206BACKGROUND

  • Iskander NG, Anderson Penno E, Peters NT, Gimbel HV, Ferensowicz M. Accuracy of Orbscan pachymetry measurements and DHG ultrasound pachymetry in primary laser in situ keratomileusis and LASIK enhancement procedures. J Cataract Refract Surg. 2001 May;27(5):681-5. doi: 10.1016/s0886-3350(01)00820-3.

    PMID: 11377895BACKGROUND

  • Altan-Yaycioglu R, Pelit A, Akova YA. Comparison of ultrasonic pachymetry with Orbscan in corneal haze. Graefes Arch Clin Exp Ophthalmol. 2007 Dec;245(12):1759-63. doi: 10.1007/s00417-007-0578-5. Epub 2007 Jun 22.

    PMID: 17583820DERIVED

MeSH Terms

Conditions

Corneal OpacityKeratitisTrachoma

Condition Hierarchy (Ancestors)

Corneal DiseasesEye DiseasesConjunctivitis, BacterialEye Infections, BacterialBacterial InfectionsBacterial Infections and MycosesInfectionsChlamydia InfectionsChlamydiaceae InfectionsGram-Negative Bacterial InfectionsEye InfectionsConjunctivitisConjunctival Diseases

Study Officials

  • Rana Altan-Yaycioglu, M.D.

    Baskent University, Faculty of Medicine, Department of Ophthalmology

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
DEFINED POPULATION
Time Perspective
OTHER
Sponsor Type
OTHER

Study Record Dates

First Submitted

February 21, 2007

First Posted

February 23, 2007

Study Start

July 1, 2005

Study Completion

June 1, 2006

Last Updated

February 23, 2007

Record last verified: 2007-02

Locations

TU(1)