NCT00402155

Brief Summary

Reading can be an uncomfortable and difficult task for some people. Symptoms include unpleasant somatic and perceptual effects, such as eye-strain, headache, and blurred text, despite normal visual acuity. This condition has been called Visual Discomfort, but little is known about the symptoms and frequency of reading problems associated with this disorder. Several studies have proposed that Visual Discomfort is caused by increased noise in the visual system due to spreading cortical activation across different spatial frequency channels. This study examines the prevalence and severity of visual discomfort in a college student population and tests the noisy visual system hypothesis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jul 2004

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2004

Completed
2.4 years until next milestone

First Submitted

Initial submission to the registry

November 17, 2006

Completed
5 days until next milestone

First Posted

Study publicly available on registry

November 22, 2006

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2008

Completed
Last Updated

November 13, 2009

Status Verified

January 1, 2009

First QC Date

November 17, 2006

Last Update Submit

November 11, 2009

Conditions

Visual Fatigue

Keywords

electroretinogramvisual evoked potentialcontrast sensitivity

Study Arms (2)

1

Normal subjects

Behavioral: Stress on visual discomfort

2

Reading discomfort subjects

Behavioral: Stress on visual discomfort

Interventions

Stress on visual discomfortBEHAVIORAL

Effects of visual discomfort are measured by contrast sensitivity, ERGs, and accommodative stability.

12

Eligibility Criteria

Age17 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Subjects will be chosen from the student population and Claremont McKenna College.

You may qualify if:

  • normal College age subjects with low visual discomfort scores on the Conlon visual discomfort survey.
  • normal College age subjects with high visual discomfort scores on the Conlon visual discomfort survey.

You may not qualify if:

  • English as a second language, uncorrected visual defects, reading disabilities, medical conditions that might cause uncomfortable visual symptoms, strabismus, stereopsis less than 70 seconds of arc, any ocular pathology, color vision deficiency, IQ less than 90.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Claremont McKenna College

Claremont, California, 91711, United States

Location

MeSH Terms

Conditions

Asthenopia

Condition Hierarchy (Ancestors)

Eye Diseases

Study Officials

  • Chris Chase, PhD

    Claremont McKenna College

    PRINCIPAL INVESTIGATOR

  • William H. Ridder,III, OD, PhD

    Southern California College of Optometry at Marshall B. Ketchum University

    STUDY DIRECTOR

  • Eric Borsting, OD, MS

    Southern California College of Optometry at Marshall B. Ketchum University

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

November 17, 2006

First Posted

November 22, 2006

Study Start

July 1, 2004

Study Completion

December 1, 2008

Last Updated

November 13, 2009

Record last verified: 2009-01

Locations

US(1)