Evaluation of New Color Temperature Adjustment Mode in Preventing Dry Eye and Visual Fatigue

NCT07201493 | Enrolling By Invitation

• 1 other identifier: TREC2025-KY185
• Study Type: interventional
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study was to investigate the effects of visual fatigue and dry eye level under different correlated color temperature modes, and to evaluate the effect of new designed dynamic color temperature change modes on the improvement of visual fatigue and dry eye level.

Conditions

Visual Fatigue; Dry Eye

Keywords

visual fatigue; tear break-up time; dry eye; VDT syndrome; critical flicker fusion frequency

Outcome Measures

Primary Outcomes (1)

• Critical flicker fusion frequency

  Critical flicker fusion frequency was measured before and after the task by a flicker fusion frequency detection device to assess changes in the degree of ocular fatigue. To compare the difference in CFF after wearing anti-blue glasses with normal glasses and to evaluate the effect of anti-blue glasses in preventing asthenopia.

  Participants underwent three randomized experimental conditions through study completion, an average of 1 months. For each condition, CFF test was administered at baseline (pre-experiment) and post-task,totaling six completions per participant.

Secondary Outcomes (3)

• Visual fatigue

  Participants underwent three randomized experimental conditions through study completion, an average of 1 months. For each condition, visual fatigue test was administered at baseline and post-task,totaling six completions per participant.

• tear break-up time

  Participants underwent three randomized experimental conditions through study completion, an average of 1 months. For each condition, CFF test was administered at baseline (pre-experiment) and post-task,totaling six completions per participant.

• Measurement of Accommodative Sensitivity with Flip-Chart Post-VDT Tasks

  Participants underwent three randomized experimental conditions through study completion, an average of 1 months. For each condition, CFF test was administered at baseline (pre-experiment) and post-task,totaling six completions per participant.

Other Outcomes (1)

• equivalent refraction

  Participants underwent three randomized experimental conditions through study completion, an average of 1 months. For each condition, CFF test was administered at baseline (pre-experiment) and post-task,totaling six completions per participant.

Study Arms (3)

6500K group

NO INTERVENTION

This is the group that performs visual evoked tasks using conventional color temperature mode of whose vaule is 6500K. In this group, the impact of the same text content on the visual fatigue and comphrehensive analysis of tear film were assessed, including but not limited to indicators such as blinking detection, visual function and so on.

sigmoid change group

EXPERIMENTAL

This is the group that performs visual evoked tasks using dynamic color temperature change mode 1 which changes from 6500K to 4000K. In this group, the impact of the same text content on the visual fatigue and comphrehensive analysis of tear film were assessed, including but not limited to indicators such as blinking detection, visual function and so on.

Behavioral: color temperature change mode

gradient change group

EXPERIMENTAL

This is the group that performs visual evoked tasks using dynamic color temperature change mode 2 which changes from 6500K to 4000K. In this group, the impact of the same text content on the visual fatigue and comphrehensive analysis of tear film were assessed, including but not limited to indicators such as blinking detection, visual function and so on.

Behavioral: color temperature change mode

Interventions

color temperature change mode BEHAVIORAL

Subjects are asked to read a terminal display device for 50 minutes, featuring texts with different color temperature mode treatments. Specifically, they will read the same text content for 50 minutes with different color temperature mode. The participants will complete a total of 2 sets of tests in a random order.

gradient change group; sigmoid change group

Eligibility Criteria

• Age: 20 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Adult population, regardless of gender.
• Refractive error is less than or equal to -1.5D and both eyes achievecorrected visual acuity of 0.8 or higher.
• Normal intraocular pressure with no organic pathology.
• No apparent symptoms of dry eye.
• Willing to cooperate to complete all the tests.
• Voluntarily signing the informed consent form.

You may not qualify if:

• Individuals with strabismus and amblyopia exist.
• Suffering from congenital eye conditions such as congenital cataracts or congenital retinal diseases.
• Those who have undergone intraocular surgery (such as cataract removal, intraocular lens implantation, etc.).
• Individuals with refractive media opacity (such as corneal lesions, lens opacity, etc.).
• Active corneal infections such as bacterial, fungal, viral, or other acute or chronic anterior segment inflammations.
• Currently using medications that may lead to dry eye or affect vision and corneal curvature.
• Other ocular conditions, such as dacryocystitis, eyelid disorders and abnormalities, abnormal intraocular pressure, and glaucoma.
• Unable to undergo regular eye examinations.

Sponsors & Collaborators

• Beijing Tongren Hospital: lead

Study Sites (1)

Beijing Tongren Hospitol,Capital Medical University,, Beijing, Beijing/China

Beijing, Beijing Municipality, 100730, China

Location

MeSH Terms

Conditions

Asthenopia; Dry Eye Syndromes

Condition Hierarchy (Ancestors)

Eye Diseases; Lacrimal Apparatus Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: In order to eliminate the influence of subjective factors during the examination, this study was blinded only to the participant.
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: This study is designed with a total of three groups, where participants will sequentially and randomly undergo all the intervention procedures.

Study Record Dates

• First Submitted: September 20, 2025
• First Posted: October 1, 2025
• Study Start: September 15, 2025
• Primary Completion: October 15, 2025
• Study Completion: December 1, 2025
• Last Updated: October 1, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)