NCT00374894

Brief Summary

Lead poisoning remains a common disease among children despite successful public health efforts that reduced its prevalence.Our study was designed to test the hypothesis that lead-poisoning children (BLLs:100-440µg/L) who were given DMSA and multi-nutrients would have a greater fall than children of other groups at 12 weeks of follow-up.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2004

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2004

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2004

Completed
2.1 years until next milestone

First Submitted

Initial submission to the registry

September 11, 2006

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 12, 2006

Completed
Last Updated

September 12, 2006

Status Verified

April 1, 2004

First QC Date

September 11, 2006

Last Update Submit

September 11, 2006

Conditions

Lead Poisoning

Keywords

2,3-dimercaptosuccinic acidBlood Lead Levelschildrenmulti-nutrients

Interventions

2,3-dimercaptosuccinic acidDRUG

Eligibility Criteria

Age3 Years - 6 Years
Sexall
Age GroupsChild (0-17)

You may qualify if:

  • Initial BLLs 100-440µg/L
  • Age 3-6y
  • No more than two main residences
  • House cleaned (no lead contaminated)
  • Normal intake history and physical

You may not qualify if:

  • Chelation in the past 12 weeks
  • Concomitant Fe deficiency(ferritin\<16ng/ml)
  • Hemoglobin\<10.5g/dL
  • Medications affecting mineral metabolism

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

China Medical University

Shenyang, Liaoning, 110001, China

Location

Related Publications (1)

  • CDC．Preventing lead poisoning in young children［R］. U.D.Dept of health and Human services 1991:1.

    RESULT

MeSH Terms

Conditions

Lead Poisoning

Interventions

Succimer

Condition Hierarchy (Ancestors)

Heavy Metal PoisoningPoisoningChemically-Induced Disorders

Intervention Hierarchy (Ancestors)

SuccinatesDicarboxylic AcidsAcids, AcyclicCarboxylic AcidsOrganic ChemicalsSulfhydryl CompoundsSulfur Compounds

Study Officials

  • Jin Ya ping, professor

    Department of Environmental and Occupational Health

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
DEFINED POPULATION
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 11, 2006

First Posted

September 12, 2006

Study Start

March 1, 2004

Study Completion

August 1, 2004

Last Updated

September 12, 2006

Record last verified: 2004-04

Locations

CN(1)