NCT00014885

Brief Summary

This project studies the relationship between lead exposure and academic achievement in college students. Most studies of the neurobehavioral effects of lead have focused on performances at the low end of the distribution. There is evidence that lead affects outcome across the entire distribution. This is a retrospective cohort study of subjects whose cognitive function is adequate to gain admission to college. We will use x-ray fluorescence to measure bone lead concentrations in undergraduate college students and test the hypothesis that achievement scores are related to early lead exposure. Early lead exposure has been shown to have measurable effects on academic performance and neurobehavioral outcomes at 18 years of age. Should an effect be found in this study, the spectrum of lead toxicity would be expanded to include subjects with above average function.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
750

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 1998

Typical duration for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 1998

Completed
2.6 years until next milestone

First Submitted

Initial submission to the registry

April 12, 2001

Completed
1 day until next milestone

First Posted

Study publicly available on registry

April 13, 2001

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2001

Completed
Last Updated

March 23, 2006

Status Verified

March 1, 2006

First QC Date

April 12, 2001

Last Update Submit

March 22, 2006

Conditions

Lead Poisoning

Keywords

Lead exposureBone leadCognitive functionAcademic achievementNeurobehavior

Eligibility Criteria

Age18 Years - 24 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Current undergraduate student at the University of Pittsburgh who have taken the Scholastic Aptitude Test (SAT).

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

MeSH Terms

Conditions

Lead Poisoning

Condition Hierarchy (Ancestors)

Heavy Metal PoisoningPoisoningChemically-Induced Disorders

Study Design

Study Type
observational
Time Perspective
RETROSPECTIVE
Sponsor Type
NIH

Study Record Dates

First Submitted

April 12, 2001

First Posted

April 13, 2001

Study Start

September 1, 1998

Study Completion

August 1, 2001

Last Updated

March 23, 2006

Record last verified: 2006-03