NCT00371787

Brief Summary

To evaluate the performance of the study soft lens for vision, comfort, physiology and lens surface properties.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
38

participants targeted

Target at below P25 for phase_3

Timeline
Completed

Started Aug 2006

Shorter than P25 for phase_3

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2006

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

September 1, 2006

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 4, 2006

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2007

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2007

Completed
3 years until next milestone

Results Posted

Study results publicly available

December 13, 2010

Completed
Last Updated

January 10, 2011

Status Verified

January 1, 2011

Enrollment Period

1.3 years

First QC Date

September 1, 2006

Results QC Date

November 8, 2010

Last Update Submit

January 5, 2011

Conditions

Outcome Measures

Primary Outcomes (4)

  • Visual Acuity

    level of vision measured using high contrast acuity chart, higher (more positive)logMAR indicates worse vision.

    baseline

  • Visual Acuity

    level of vision measured using high contrast acuity chart, higher (more positive)logMAR indicates worse vision.

    9 month

  • Neovascularisation

    length of the blood vessels entering the superior cornea, higher number means longer blood vessel penetration.

    baseline

  • Neovascularization

    length of the blood vessels entering the superior cornea, higher number means longer blood vessel penetration.

    9 month

Study Arms (2)

soft contact lens

EXPERIMENTAL
Device: Soft contact lens

non-lens wear

NO INTERVENTION

control group

Interventions

Soft contact lens

Also known as: Custom O2Optix
soft contact lens

Eligibility Criteria

Age17 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Male or female, good health, age \>17yrs, able to wear contact lenses as primary vision correction, able to see well and achieve good fit with study lens, has understood \& signed consent form.

You may not qualify if:

  • Has active ocular disease, uses topical eye medication, wears gas permeable/silicone hydrogel /overnight wear contact lenses, is a participant in another clinical study, is deemed unsuitable for soft contact lens wear.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre for Contact Lens Research, University of Waterloo,

Waterloo, Ontario, N2L 3G1, Canada

Location

MeSH Terms

Conditions

Refractive Errors

Interventions

Contact Lenses, Hydrophilic

Condition Hierarchy (Ancestors)

Eye Diseases

Intervention Hierarchy (Ancestors)

Contact LensesLensesOptical DevicesEquipment and Supplies

Results Point of Contact

Title
Dr. Craig Woods
Organization
Centre for Contact Lens Research

Study Officials

  • Desmond Fonn

    Centre for Contact Lens Research

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
phase 3
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 1, 2006

First Posted

September 4, 2006

Study Start

August 1, 2006

Primary Completion

December 1, 2007

Study Completion

December 1, 2007

Last Updated

January 10, 2011

Results First Posted

December 13, 2010

Record last verified: 2011-01

Locations