NCT00342810

Brief Summary

Since 1948, the Framingham Study has examined a group of men and women every two years for the primary purpose of studying the incidence and prevalence of cardiovascular disease and its risk factors. In 1971 the Framingham Study began a study of the offspring of the original group, including data collection on blood pressure, cigarette smoking, weight, and other factors that are of interest to studies of eye disease. Researchers gave eye exams to some of the original group and to the offspring group. Data from these eye exams have been used to examine risk factors for cataracts, diabetic retinopathy, myopia, and glaucoma. The purpose of this study is to use the previously collected data for continued research on eye-related disorders. No new eye examinations will be conducted. ...

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
6,061

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2003

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 25, 2003

Completed
3 years until next milestone

First Submitted

Initial submission to the registry

June 19, 2006

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 21, 2006

Completed
11.9 years until next milestone

Study Completion

Last participant's last visit for all outcomes

April 25, 2018

Completed
Last Updated

December 17, 2019

Status Verified

April 25, 2018

First QC Date

June 19, 2006

Last Update Submit

December 14, 2019

Conditions

Eye Diseases

Keywords

Eye Diseases

Outcome Measures

Primary Outcomes (1)

  • Explore associations using study data

    Continuous

Eligibility Criteria

Age30 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
* This study is of existing ocular data from the Framingham Eye Study. Since the participants have already been recruited, there are no further exclusions from the study.

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

National Eye Institute (NEI), 9000 Rockville Pike

Bethesda, Maryland, 20892, United States

Location

Related Publications (3)

  • Ederer F, Hiller R, Taylor HR. Senile lens changes and diabetes in two population studies. Am J Ophthalmol. 1981 Mar;91(3):381-95. doi: 10.1016/0002-9394(81)90293-2.

    PMID: 7211996BACKGROUND

  • Sperduto RD, Hiller R. The prevalence of nuclear, cortical, and posterior subcapsular lens opacities in a general population sample. Ophthalmology. 1984 Jul;91(7):815-8. doi: 10.1016/s0161-6420(84)34233-6.

    PMID: 6472815BACKGROUND

  • Hiller R, Sperduto RD, Podgor MJ, Ferris FL 3rd, Wilson PW. Diabetic retinopathy and cardiovascular disease in type II diabetics. The Framingham Heart Study and the Framingham Eye Study. Am J Epidemiol. 1988 Aug;128(2):402-9. doi: 10.1093/oxfordjournals.aje.a114980.

    PMID: 3293436BACKGROUND

MeSH Terms

Conditions

Eye Diseases

Study Officials

  • Susan Vitale, Ph.D.

    National Eye Institute (NEI)

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
NIH
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 19, 2006

First Posted

June 21, 2006

Study Start

June 25, 2003

Study Completion

April 25, 2018

Last Updated

December 17, 2019

Record last verified: 2018-04-25

Locations

US(1)