NCT00327821

Brief Summary

The objective is to compare the effectiveness of 4 different commercial weight-loss diets available to adults in the UK. This is achieved with a 6 month multi-centre randomised unblinded controlled trial of

  • Dr Atkins' New Diet Revolution,
  • The slimFast Plan,
  • The weight Watchers Pure Points Programme,
  • Rosemary Conley's "Eat Yourself Slim" Diet \& Fitness Plan.
  • No diet (control) Subjects are a community based sample of 300 (60 per group) otherwise healthy overweight and obese adults. Main outcome measures are weight and body fat change over 6 months.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for not_applicable obesity

Timeline
Completed

Started Jul 2002

Shorter than P25 for not_applicable obesity

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2002

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2003

Completed
3.2 years until next milestone

First Submitted

Initial submission to the registry

May 17, 2006

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 19, 2006

Completed
Last Updated

July 21, 2006

Status Verified

May 1, 2003

First QC Date

May 17, 2006

Last Update Submit

July 20, 2006

Conditions

Outcome Measures

Primary Outcomes (2)

  • Weight loss

  • Fat loss

Interventions

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Body mass index (BMI) \> 27 and \< 40 kg/m2.

You may not qualify if:

  • History of coronary heart disease
  • Type 1 or Type 2 diabetes
  • Renal, liver or respiratory failure
  • Gout
  • Taking lipid lowering or anti-hypertensive drugs
  • History of obesity with known cause (i.e. Cushings disease, hypothyroidism)
  • Previous gastric or weight loss surgery
  • Taking any weight loss drug (including Orlistat or Sibutramine)
  • Clinical depression
  • Eating disorders
  • Drug or alcohol abuse
  • Any malabsorptive state (including lactose intolerance)
  • Being treated for a malignancy
  • Being pregnant
  • Breastfeeding

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Surrey

Guildford, surrey, GU2 7XH, United Kingdom

Location

Related Publications (2)

  • Truby H, Baic S, deLooy A, Fox KR, Livingstone MB, Logan CM, Macdonald IA, Morgan LM, Taylor MA, Millward DJ. Randomised controlled trial of four commercial weight loss programmes in the UK: initial findings from the BBC "diet trials". BMJ. 2006 Jun 3;332(7553):1309-14. doi: 10.1136/bmj.38833.411204.80. Epub 2006 May 23.

  • Truby H, Hiscutt R, Herriot AM, Stanley M, Delooy A, Fox KR, Baic S, Robson PJ, Macdonald I, Taylor MA, Ware R, Logan C, Livingstone M. Commercial weight loss diets meet nutrient requirements in free living adults over 8 weeks: a randomised controlled weight loss trial. Nutr J. 2008 Sep 2;7:25. doi: 10.1186/1475-2891-7-25.

MeSH Terms

Conditions

Obesity

Interventions

Caloric Restriction

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Diet TherapyNutrition TherapyTherapeuticsEnergy IntakeDietNutritional Physiological PhenomenaDiet, Food, and NutritionPhysiological Phenomena

Study Officials

  • D J Millward, PhD

    University of Surrey

    PRINCIPAL INVESTIGATOR
  • H A Truby, PhD SRD

    University of Surrey

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 17, 2006

First Posted

May 19, 2006

Study Start

July 1, 2002

Study Completion

March 1, 2003

Last Updated

July 21, 2006

Record last verified: 2003-05

Locations