The Effects of a 16-Week Individualized, Intensive Strength Training Program in Patients With Rheumatoid Arthritis

NCT00327275 | Completed

• 1 other identifier: 080192
• Study Type: interventional
• Target: 35
• Locations: 1 country
• Sites: 1

Brief Summary

To assess the effects of a 16-week individualized, intensive strength training program in patients with rheumatoid arthritis. Primary and secondary outcomes include: strength and body composition, function, disease activity, pain, quality of life. We hypothesized that improvements would be seen in all of the above outcomes.

Conditions

Rheumatoid Arthritis

Outcome Measures

Primary Outcomes (4)

• Strength

• Body Composition

• Function

• Pain

Secondary Outcomes (3)

• Quality of Life

• Disease Activity

• Fatigue

Interventions

strength training BEHAVIORAL

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Males and females with RA
• Over 18 years of age
• ACR Functional Class I and II
• Taking Remicade \>4 months

You may not qualify if:

• Presence of comorbid conditions contraindicated to exercise, including, but not limited to:
• heart disease
• severe osteoporosis: (if \>50 years): T score \< -3.0 for hip or spine excluded; T score \<-2.5 for hip or spine w/o current treatment)
• (all potential subjects) previous non-traumatic fractures
• uncontrolled BP
• BMI \>40
• Regular use of assistive walking device which would interfere with ability to lift weights
• Currently or within the last 3 months participating in aerobic exercise \> 150 minutes a week
• Currently or within the last 3 months participating in any regular strength training activities
• Presence of neurological impairment that directly limits ability to perform exercise
• Participation in concurrent exercise study
• Any reason for which the investigator deems it would not be in the patient's best interest to continue in the study
• Plans to move away from site within next 1 year

Sponsors & Collaborators

• University of Arizona: lead
• Centocor, Inc.: collaborator

Study Sites (1)

University of Arizona

Tucson, Arizona, 85721, United States

Location

MeSH Terms

Conditions

Arthritis, Rheumatoid

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Connective Tissue Diseases; Skin and Connective Tissue Diseases; Autoimmune Diseases; Immune System Diseases

Intervention Hierarchy (Ancestors)

Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Hilary G Flint-Wagner, PhD, MPH

  Idaho State University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: May 16, 2006
• First Posted: May 18, 2006
• Study Start: March 1, 2004
• Study Completion: January 1, 2005
• Last Updated: May 18, 2006

Record last verified: 2006-05

Locations

US (1)