NCT00311259

Unknown

Melatonin Treatment and Inflammation, Oxidative Stress and A...

University Hospital, Gentofte, Copenhagen Source

Compare

Other study identifiers

Sponsor study identifier

2612-3108

Study Type

observational

Reported enrollment (type unavailable)

40

Locations

1 country

Sites

1

Timeline

Study Start

May 2006

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

Not reported

Date not reported

Study Completion

November 2006

Date type not reported

This date has not been verified as actual or estimated.

Brief Summary

The purpose of this study is to determine whether treatment with melatonin can reduce cell damage and inflammation in connection with laparoscopic gall bladder surgery.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: unknown
Reported enrollment (type unavailable): 40 participants
Study completion date: November 2006
Date type not reported
This date has not been verified as actual or estimated.
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

First Submitted
April 3, 2006
Actual (reported)
First Posted
April 5, 2006
Actual (reported)
Study Start
May 2006
Date type not reported
This date has not been verified as actual or estimated.
Study Completion
November 2006
Date type not reported
This date has not been verified as actual or estimated.

Last Updated: April 5, 2006
Status Verified: February 2006
Last Update Submitted: April 3, 2006

Conditions

Oxidative Stress Inflammatory Stress Myocardial Ischaemia

Interventions

Melatonin (drug)Drug

LaktoseDrug

Eligibility Criteria

Age18 Years - 70 Years

Sexfemale

Healthy VolunteersYes

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

indikation for laparoscopic cholecystectomy
women between 18 and 70 years old

You may not qualify if:

Sponsors & Collaborators

University Hospital, Gentofte, Copenhagen
Otherlead

Study Sites (1)

Department of Surgical Gastroenterology, University Hospital of Copenhagen in Gentofte

Hellerup, 2900, Denmark

Bülent KücükakinCONTACT+45 3997824 bulkuc01@gentoftehosp.kbhamt.dk

Related Publications (1)

Kucukakin B, Klein M, Lykkesfeldt J, Reiter RJ, Rosenberg J, Gogenur I. No effect of melatonin on oxidative stress after laparoscopic cholecystectomy: a randomized placebo-controlled trial. Acta Anaesthesiol Scand. 2010 Oct;54(9):1121-7. doi: 10.1111/j.1399-6576.2010.02294.x.
PMID: 20887414DERIVED

MeSH Terms

Conditions

Coronary Artery Disease

Interventions

MelatoninPharmaceutical Preparations

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Intervention Hierarchy (Ancestors)

TryptaminesIndolesHeterocyclic Compounds, 2-Ring

Study Officials

Bülent Kücükakin
Department of Surgical Gastroenterology, University Hospital of Copenhagen in Gentofte
PRINCIPAL INVESTIGATOR

Central Study Contacts

Bülent Kücükakin

CONTACT

+45 39978224 bulkuc01@gentoftehosp.kbhamt.dk

Study Design

Study Type: observational
Time Perspective: OTHER
Sponsor Type: OTHER

Study Record Dates

First Submitted

April 3, 2006

First Posted

April 5, 2006

Study Start

May 2006

Date type not reported

This date has not been verified as actual or estimated.

Study Completion

November 2006

Date type not reported

This date has not been verified as actual or estimated.

NCT05570526

Effect of Melatonin in Pediatric Hemodialysis Patients

Phase 3Unknown

NCT04318067

Melatonin in ADHD and Sleep Problems

Phase 4Unknown

NCT01805089

Melatonin Versus Placebo in Breast Cancer

Early Phase 1Completed

NCT00513357

Melatonin Versus Placebo and the Effect on Appetite in Advanced Cancer Patients

Phase 3Completed

NCT03204877

Acute Metabolic Effects of Melatonin Treatment

Phase 1/2Completed

NCT02386319

Anxiolytic and Analgesic Effects of Melatonin

Phase 3Completed

men
acute cholecystectomy
pancreatitis
renal insufficient
well-known liver insufficient
cardiovascular disease (arrhythmia, well-known ischaemic heart disease)
drug therapy (digoxin, Ca-antagonist, amiodaron, beta-blocker)
anticoagulation therapy (marevan and marcoumar)
praeoperative therapy with opioid, anxiolytica and hypnotica)
well-known sleep disease
endocrine disease in drug therapy (diabetes mellitus, thyroid disease)
daily alcohol consumption (more than 5 drinks)
bad compliance (language difficulty, mental problems etc.)
pregnancy and breast-feeding
lack of written consent

Contact the study team to confirm eligibility.

Heterocyclic Compounds, Fused-Ring

Heterocyclic Compounds

Hormones

Hormones, Hormone Substitutes, and Hormone Antagonists

Last Updated

April 5, 2006

Record last verified: 2006-02

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT00311259
Data provider: ClinicalTrials.gov
Source updated: 2006-04-05
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:31:12 UTC

Locations

DK(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Study Completion

Conditions

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

Source record

Locations