Motivating Factors That Play a Role in Bulimia Nervosa
Translational Research on Eating Disorders: Behavioral Assessment of Motivation to Eat
3 other identifiers
observational
90
1 country
1
Brief Summary
This study will evaluate whether people with bulimia nervosa will binge eat in a structured laboratory setting and display behavioral patterns similar to those of individuals who are dependent on drugs.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started May 2005
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2005
CompletedFirst Submitted
Initial submission to the registry
March 15, 2006
CompletedFirst Posted
Study publicly available on registry
March 17, 2006
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2016
CompletedMay 24, 2016
May 1, 2016
9.1 years
March 15, 2006
May 23, 2016
Conditions
Outcome Measures
Primary Outcomes (2)
Breakpoint
Measured at Day 3
Total work performed on progressive task
Measured at Day 3
Study Arms (2)
Subjects with bulimia nervosa
Participants with bulimia nervosa
Controls between 80-120% of ideal weight
Controls without bulimia nervosa
Interventions
Participants will use a computer program to earn food (a yogurt shake) by tapping on the keyboard. More taps on the keyboard will result in a larger amount of food earned by the end of the day. Once experimentation is complete on Day 1, participants will be instructed to eat as much as they can. On Days 2 and 3, participants will be given a small serving of the yogurt shake prior to beginning the computer task. Following the computer task, they will be instructed to either eat until they are comfortable (without restricting or binging), or eat as much as they can.
Eligibility Criteria
Participants who meet DSM-IV criteria for bulimia nervosa and control participants who weigh between 80 and 120% of ideal weight
You may qualify if:
- Participants with Bulimia Nervosa:
- Meets DSM-IV criteria for bulimia nervosa
- Duration of illness is greater than 1 year
- Self-induces vomiting
- Weighs between 80% and 120% of ideal weight
- Female
- Control Group:
- Weighs between 80% and 120% of ideal weight
- Female
- Ages 18-45
- No current or past psychiatric illness
- No history of eating disorder
You may not qualify if:
- Participants with Bulimia Nervosa:
- Significant medical illness
- Current Axis I illness other than major depression
- Severe or very severe depression
- At risk for suicide
- Currently taking medication
- History of drug or alcohol abuse within the 6 months prior to study entry
- Pregnant
- Male
- Control Group:
- Significant medical illness
- Currently taking medication
- History of drug or alcohol abuse within the 6 months prior to study entry
- Pregnant
- Male
- +1 more criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Eating Disorders Clinic, New York State Psychiatric Institute
New York, New York, 10032, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
B. T. Walsh, MD
New York State Psychiatric Institute at Columbia University Medical Center
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 15, 2006
First Posted
March 17, 2006
Study Start
May 1, 2005
Primary Completion
June 1, 2014
Study Completion
May 1, 2016
Last Updated
May 24, 2016
Record last verified: 2016-05