Effect of Cold Air Cooling on the Incidence of Post Inflammatory Hyperpigmentation Following Laser Treatment
1 other identifier
interventional
20
1 country
1
Brief Summary
\- To investigate the benefit of epidermal cooling on the incidence of post inflammatory hyperpigmentation after laser irradiation
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Dec 2005
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2005
CompletedFirst Submitted
Initial submission to the registry
February 2, 2006
CompletedFirst Posted
Study publicly available on registry
February 6, 2006
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2006
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2006
CompletedMay 22, 2008
February 1, 2007
4 months
February 2, 2006
May 21, 2008
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Incidence of post inflammatory hyperpigmentation
2 weeks
Secondary Outcomes (1)
Side effects of cold air cooling and clearing rate of pigmented lesion
12 weeks
Study Arms (1)
1
OTHER1= cool air cooling
Interventions
Eligibility Criteria
You may qualify if:
- Subjects with acquired bilateral nevus of Ota-like macules.
- At least 18 years old
- No previous treatment on the condition for a minimum period of 1 month.
You may not qualify if:
- Subjects diagnosed of scleroderma, connective tissue disorders, hematologic disorders, hepatitis, infection, or uncontrolled DM
- History of keloid and/or hypertrophic scar.
- Currently on anti-coagulant
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Dermatology, Siriraj Hospital, Mahidol University
Bangkok, Bangkok, 10700, Thailand
Related Publications (4)
Manuskiatti W, Sivayathorn A, Leelaudomlipi P, Fitzpatrick RE. Treatment of acquired bilateral nevus of Ota-like macules (Hori's nevus) using a combination of scanned carbon dioxide laser followed by Q-switched ruby laser. J Am Acad Dermatol. 2003 Apr;48(4):584-91. doi: 10.1067/mjd.2003.193.
PMID: 12664023BACKGROUNDKunachak S, Leelaudomlipi P, Sirikulchayanonta V. Q-Switched ruby laser therapy of acquired bilateral nevus of Ota-like macules. Dermatol Surg. 1999 Dec;25(12):938-41. doi: 10.1046/j.1524-4725.1999.99176.x.
PMID: 10594626BACKGROUNDRaulin C, Grema H. Single-pass carbon dioxide laser skin resurfacing combined with cold-air cooling: efficacy and patient satisfaction of a prospective side-by-side study. Arch Dermatol. 2004 Nov;140(11):1333-6. doi: 10.1001/archderm.140.11.1333.
PMID: 15545541BACKGROUNDManuskiatti W, Eimpunth S, Wanitphakdeedecha R. Effect of cold air cooling on the incidence of postinflammatory hyperpigmentation after Q-switched Nd:YAG laser treatment of acquired bilateral nevus of Ota like macules. Arch Dermatol. 2007 Sep;143(9):1139-43. doi: 10.1001/archderm.143.9.1139.
PMID: 17875874DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Woraphong - Manuskiatti, M.D.
Mahidol University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
February 2, 2006
First Posted
February 6, 2006
Study Start
December 1, 2005
Primary Completion
April 1, 2006
Study Completion
April 1, 2006
Last Updated
May 22, 2008
Record last verified: 2007-02