NCT00252928

Brief Summary

The purpose of this study to determine whether Aquatabs, a water treatment tablet, reduces diarrheal diseases in a peri-urban population of Tamale, Ghana.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
240

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2006

Shorter than P25 for not_applicable

Geographic Reach
2 countries

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 10, 2005

Completed
5 days until next milestone

First Posted

Study publicly available on registry

November 15, 2005

Completed
8 months until next milestone

Study Start

First participant enrolled

July 1, 2006

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2006

Completed
Last Updated

October 30, 2007

Status Verified

October 1, 2007

First QC Date

November 10, 2005

Last Update Submit

October 29, 2007

Conditions

Diarrhea

Keywords

sodium dichloroisocyanuratewater purificationdisinfectionGhana

Outcome Measures

Primary Outcomes (1)

  • Measure the impact of Aquatabs on diarrhea among persons in households in Tamale, Ghana.

    12 weeks

Secondary Outcomes (2)

  • Assess the microbiological quality of household water among persons living in Tamale, Ghana.

    12 weeks

  • Determine the acceptability of Aquatabs.

    12 weeks

Study Arms (2)

A

PLACEBO COMPARATOR

Placebo group does not receive Aquatabs.

Other: Placebo

B

EXPERIMENTAL

Intervention arms receives Aquatabs.

Other: Sodium dichloroisocyanurate (NaDCC) tablets

Interventions

Sodium dichloroisocyanurate (NaDCC) tabletsOTHER

Intervention arm receives NaDCC tablets to use for to disinfect their household water for use for 20L of water. Ideally, disinfection occurs every day.

Also known as: Aquatabs
B
PlaceboOTHER

Placebo

A

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Households with at least one child under 5 years old

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Emory University Center for Global Safe Water

Atlanta, Georgia, 30322, United States

Location

NewEnergy

Tamale, Ghana

Location

University of Development Studies

Tamale, Ghana

Location

Related Publications (5)

  • Mintz ED, Reiff FM, Tauxe RV. Safe water treatment and storage in the home. A practical new strategy to prevent waterborne disease. JAMA. 1995 Mar 22-29;273(12):948-53.

    PMID: 7884954BACKGROUND

  • Reiff FM, Roses M, Venczel L, Quick R, Witt VM. Low-cost safe water for the world: a practical interim solution. J Public Health Policy. 1996;17(4):389-408.

    PMID: 9009536BACKGROUND

  • Quick RE, Venczel LV, Mintz ED, Soleto L, Aparicio J, Gironaz M, Hutwagner L, Greene K, Bopp C, Maloney K, Chavez D, Sobsey M, Tauxe RV. Diarrhoea prevention in Bolivia through point-of-use water treatment and safe storage: a promising new strategy. Epidemiol Infect. 1999 Feb;122(1):83-90. doi: 10.1017/s0950268898001782.

    PMID: 10098789BACKGROUND

  • Quick RE, Venczel LV, Gonzalez O, Mintz ED, Highsmith AK, Espada A, Damiani E, Bean NH, De Hannover EH, Tauxe RV. Narrow-mouthed water storage vessels and in situ chlorination in a Bolivian community: a simple method to improve drinking water quality. Am J Trop Med Hyg. 1996 May;54(5):511-6. doi: 10.4269/ajtmh.1996.54.511.

    PMID: 8644907BACKGROUND

  • Sobel J, Mahon B, Mendoza CE, Passaro D, Cano F, Baier K, Racioppi F, Hutwagner L, Mintz E. Reduction of fecal contamination of street-vended beverages in Guatemala by a simple system for water purification and storage, handwashing, and beverage storage. Am J Trop Med Hyg. 1998 Sep;59(3):380-7. doi: 10.4269/ajtmh.1998.59.380.

    PMID: 9749629BACKGROUND

MeSH Terms

Conditions

Diarrhea

Interventions

trocloseneTablets

Condition Hierarchy (Ancestors)

Signs and Symptoms, DigestiveSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Dosage FormsPharmaceutical Preparations

Study Officials

  • Seema Jain, MD

    Centers for Disease Control and Prevention

    PRINCIPAL INVESTIGATOR

  • Robert Quick, MD

    Centers for Disease Control and Prevention

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR
Purpose
PREVENTION
Intervention Model
FACTORIAL
Sponsor Type
FED

Study Record Dates

First Submitted

November 10, 2005

First Posted

November 15, 2005

Study Start

July 1, 2006

Study Completion

November 1, 2006

Last Updated

October 30, 2007

Record last verified: 2007-10

Locations

GH(2)US(1)