Cognitive Processing Therapy Versus Its Individual Components in the Treatment of Post-Traumatic Stress Disorder and Depression in Women Who Have Been Sexually Abused
Cognitive Processes in PTSD: Treatment
2 other identifiers
interventional
228
1 country
1
Brief Summary
This study will evaluate the effectiveness of cognitive processing therapy versus its individual components in treating women with post-traumatic stress disorder (PTSD) and depression brought on by sexual assault.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Aug 2000
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2000
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2005
CompletedFirst Submitted
Initial submission to the registry
October 25, 2005
CompletedFirst Posted
Study publicly available on registry
October 27, 2005
CompletedMarch 31, 2015
March 1, 2015
October 25, 2005
March 30, 2015
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Depression symptoms; measured immediately post-treatment and 6 months post-treatment
Post-traumatic stress disorder symptoms; measured immediately post-treatment and 6 months post-treatment
Interventions
Eligibility Criteria
You may qualify if:
- History of a discrete episode of assault in childhood or adulthood
- Meets criteria for post-traumatic stress disorder
You may not qualify if:
- Experienced a traumatic event that was in the form of chronic ongoing abuse and not a discrete incidence
- Psychosis
- Mental retardation
- Suicidal or parasuicidal
- Currently addicted to drugs
- Illiterate
- Currently in an abusive relationship
- Currently being stalked
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Center for Trauma and Recovery, University of Missouri - St. Louis
St Louis, Missouri, 63121-4499, United States
Related Publications (3)
Resick PA, Nishith P, Weaver TL, Astin MC, Feuer CA. A comparison of cognitive-processing therapy with prolonged exposure and a waiting condition for the treatment of chronic posttraumatic stress disorder in female rape victims. J Consult Clin Psychol. 2002 Aug;70(4):867-79. doi: 10.1037//0022-006x.70.4.867.
PMID: 12182270RESULTO'Doherty L, Whelan M, Carter GJ, Brown K, Tarzia L, Hegarty K, Feder G, Brown SJ. Psychosocial interventions for survivors of rape and sexual assault experienced during adulthood. Cochrane Database Syst Rev. 2023 Oct 5;10(10):CD013456. doi: 10.1002/14651858.CD013456.pub2.
PMID: 37795783DERIVEDFitzpatrick SS, Liebman RE, Monson CM, Resick PA. Latent emotion profiles of PTSD and specific emotions predicting differential therapy outcomes in a dismantling study of cognitive processing therapy. J Anxiety Disord. 2023 Apr;95:102681. doi: 10.1016/j.janxdis.2023.102681. Epub 2023 Feb 17.
PMID: 36848714DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Patricia A. Resick, PhD
National Center for PTSD, Women's Health Sciences Division
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
October 25, 2005
First Posted
October 27, 2005
Study Start
August 1, 2000
Study Completion
April 1, 2005
Last Updated
March 31, 2015
Record last verified: 2015-03