SPECT/CT in Endocrine and Neuroendocrine Tumors

NCT00230139 | Completed

• 1 other identifier: endocrineCTIL
• Study Type: interventional
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

The value of fusion of functional and anatomical data has been described using several fusion techniques for various nuclear medicine procedures and morphologic imaging modalities (SPECT-CT, SPECT-MRI, Coincidence-CT). We hypothesize that NM -CT data has advantages over the data obtained using separately performed NM study and conventional anatomic imaging as CT. We hypothesize that more accurate localization of the radio-isotope activity on NM images will improve diagnostic accuracy and will have an impact on patient management: Improved accuracy of NM study will improve tumor localization, the evaluation of the extent of disease and the post therapy follow up. It will direct other diagnostic procedures to lesions otherwise undetected, or exclude the need for more invasive procedures. It can also guide invasive procedures and radiation-therapy planning, thus improving therapy results and avoiding unnecessary treatment-related side effects.

Conditions

Endocrine and Neuroendocrine Tumors

Outcome Measures

Primary Outcomes (1)

• The impact of imaging modality on patient management

Secondary Outcomes (1)

• The impact of imaging modality on patient management

Interventions

SPECT/CT DEVICE

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patient referred for NM scintigraphy to assess the presence of endocrine or neuroendocrine tumors.
• Patient signed informed consent

You may not qualify if:

• The study will not be performed in pregnant or lactating women.
• Patient will not be able or willing to tolerate the scan until its completion.

Sponsors & Collaborators

• Rambam Health Care Campus: lead

Study Sites (1)

Rambam Medical Center

Haifa, Israel

Location

MeSH Terms

Conditions

Neuroendocrine Tumors

Interventions

Single Photon Emission Computed Tomography Computed Tomography

Condition Hierarchy (Ancestors)

Neuroectodermal Tumors; Neoplasms, Germ Cell and Embryonal; Neoplasms by Histologic Type; Neoplasms; Neoplasms, Nerve Tissue

Intervention Hierarchy (Ancestors)

Tomography, Emission-Computed, Single-Photon; Tomography, Emission-Computed; Image Interpretation, Computer-Assisted; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Tomography, X-Ray Computed; Multimodal Imaging; Radiographic Image Enhancement; Image Enhancement; Photography; Radiography; Tomography, X-Ray; Radionuclide Imaging; Tomography; Diagnostic Techniques, Radioisotope

Study Officials

• Zohar Keidar, MD,PhD

  Rambam Health Care Campus

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: September 29, 2005
• First Posted: September 30, 2005
• Study Start: January 1, 2002
• Primary Completion: January 1, 2004
• Study Completion: January 1, 2006
• Last Updated: October 15, 2008

Record last verified: 2005-09

Locations

IL (1)