NCT00194220

Completed

Infertility Markers in Serum, Urine, and Follicular Fluid

University of Pennsylvania Source

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Other study identifiers

Sponsor study identifier

706658

Secondary identifiers

RRU011

Study Type

observational

Actual enrollment (reported)

1,235

Locations

1 country

Sites

1

Timeline

Study Start

September 2002

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

July 2012

Actual (reported)

Study Completion

February 2013

Actual (reported)

Brief Summary

This study is only collecting specimens from current patients of PENN Fertility Care. The purpose of this investigation is to assess if markers of oxidative stress that are known to be associated with other medical conditions can be detected in women undergoing infertility treatment and normal women of similar age. Oxidative stress may affect a woman's eggs or the follicular cells that surround and nurture them. Other markers of to be investigated include markers of cellular aging and DNA structural changes. Presence of these markers will be compared in blood and urine samples taken during infertility treatment, and follicular fluid at the time of IVF (if applicable).

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Actual enrollment (reported): 1,235 participants
Study completion date: February 2013
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
September 2002
Date type not reported
This date has not been verified as actual or estimated.
First Submitted
September 13, 2005
Actual (reported)
First Posted
September 19, 2005
Actual (reported)
Primary Completion
July 2012
Actual (reported)
Study Completion
February 2013
Actual (reported)

Last Updated: September 30, 2015
Status Verified: September 2015
Last Update Submitted: September 28, 2015

Conditions

Infertility

Keywords

InfertilityOxidative stress

Eligibility Criteria

Age18 Years - 50 Years

Sexfemale

Healthy VolunteersYes

Age GroupsAdult (18-64)

Sampling MethodNon-Probability Sample

Study Population

Women undergoing In vitro fertilization at the University of Pennsylvania

You may qualify if:

Women aged 18-50
Infertility patients only:
Women undergoing infertility treatment (with or without in-vitro fertilization) at the University of Pennsylvania's PENN Fertility Care
Verified infertility diagnosis of any of the following:
Endometriosis (minimal or mild)

Sponsors & Collaborators

University of Pennsylvania
Otherlead

Study Sites (1)

University of Pennsylvania Reproductive Research Unit

Philadelphia, Pennsylvania, 19104, United States

Biospecimen

Retention: SAMPLES WITH DNA

Blood, Urine, Follicular Fluid

MeSH Terms

Conditions

Infertility

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Study Officials

Kurt T Barnhart, MD, MSCE
University of Pennsylvania
PRINCIPAL INVESTIGATOR

Enrollment

1,235 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

September 13, 2005

First Posted

September 19, 2005

Study Start

September 2002

Date type not reported

This date has not been verified as actual or estimated.

Infertility Therapy for Women Age Thirty-eight and Older

Not ApplicableUnknown

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Conventional Infertility Treatment vs. Fast Track to IVF

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NCT00372658

Intracervical Block Versus Placebo to Assess Pain Control During Hysterosalpingogram

Phase 2Completed

NCT07154888

Fast Track to Fertility

Not ApplicableCompleted

NCT00656201

Comparison of Crinone 8% Intravaginal Gel and IM Progesterone Supplementation for In Vitro Fertilization (IVF)

Phase 4Completed

Endometriosis (moderate or severe)

Tubal factor

Hypogonadotrophic hypogonadism

Polycystic ovary syndrome

Diminished ovarian reserve

Male factor

Unexplained

Healthy normal volunteers only:

Not undergoing infertility treatment

Not using hormonal contraception

You may not qualify if:

Currently pregnant or breastfeeding
Post-menopausal
Concurrent participation in investigational trial
Other health problems which, in the opinion of the investigator, may affect participation

Contact the study team to confirm eligibility.

Primary Completion

July 2012

Actual (reported)

Study Completion

February 2013

Actual (reported)

Last Updated

September 30, 2015

Record last verified: 2015-09

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT00194220
Data provider: ClinicalTrials.gov
Source updated: 2015-09-30
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:40:51 UTC

Locations

US(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations