NCT00113867

Completed

Effects of Hormonal Infertility Treatment on Cognition in Pr...

National Institute on Aging (NIA)Source

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Other study identifiers

Sponsor study identifier

AG0022

Study Type

observational

Reported enrollment (type unavailable)

80

Locations

1 country

Sites

1

Timeline

Study Start

September 2003

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

November 2006

Actual (reported)

Study Completion

November 2006

Actual (reported)

Brief Summary

The purpose of this study is to examine the effects of marked alterations in ovarian steroid hormones on cognitive functions in women. Sex hormones and stress hormones of women awaiting or undergoing in-vitro fertilization (IVF) will be compared with levels of women adopting children and women on oral contraceptives.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Reported enrollment (type unavailable): 80 participants
Study completion date: November 2006
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
September 2003
Date type not reported
This date has not been verified as actual or estimated.
First Submitted
June 10, 2005
Actual (reported)
First Posted
June 13, 2005
Actual (reported)
Primary Completion
November 2006
Actual (reported)
Study Completion
November 2006
Actual (reported)

Last Updated: December 11, 2009
Status Verified: November 2006
Last Update Submitted: December 9, 2009

Conditions

Infertility

Keywords

IVFin vitro fertilizationhormonesstressmemoryCognitive Functionadoption

Eligibility Criteria

Age25 Years+

Sexfemale

Healthy VolunteersYes

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Women 25 years and older, who are still ovulating
Residing in Maryland or the Washington DC metropolitan area
Healthy women in one of the following groups:
\) beginning or currently undergoing IVF infertility treatments with GnRH-a alone,
\) beginning or currently undergoing IVF infertility treatments with GnrH-a plus sex steroid stimulating hormones,

Sponsors & Collaborators

National Institute on Aging (NIA)
NIHlead

Study Sites (1)

National Institute on Aging (NIA), Harbor Hospital

Baltimore, Maryland, 21225, United States

Related Publications (3)

Sherwin BB, Tulandi T. "Add-back" estrogen reverses cognitive deficits induced by a gonadotropin-releasing hormone agonist in women with leiomyomata uteri. J Clin Endocrinol Metab. 1996 Jul;81(7):2545-9. doi: 10.1210/jcem.81.7.8675575.
PMID: 8675575BACKGROUND
Harlow CR, Fahy UM, Talbot WM, Wardle PG, Hull MG. Stress and stress-related hormones during in-vitro fertilization treatment. Hum Reprod. 1996 Feb;11(2):274-9. doi: 10.1093/humrep/11.2.274.
PMID: 8671208BACKGROUND

MeSH Terms

Conditions

Infertility

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Study Officials

Melissa H. Kitner-Triolo, PhD
Research Psychologist, Laboratory of Personality & Cognition, Cognition Section, Intramural Reserach Program, National Institute on Aging, National Institutes of Health
PRINCIPAL INVESTIGATOR

Study Design

Study Type: observational
Sponsor Type: NIH

Study Record Dates

First Submitted

June 10, 2005

First Posted

June 13, 2005

Study Start

September 2003

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

November 2006

Actual (reported)

NCT00361816

Human MATER and Idiopathic Infertility

Completed

NCT00378001

Clinical Efficacy and Tolerability of Two FSH Preparations (Human FSH Versus rFSH - Follitropin Alpha) in Women Undergoing IVF

Phase 3Completed

NCT00296465

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Three Dosage Strengths of Pulsatile GnRH

Phase 2/3Completed

NCT00736411

In Vitro Fertilization (IVF) and Acupuncture for Infertility

Not ApplicableTerminated

NCT00225433

Luteal Phase FSH in the IVF Poor Responder

Phase 4Completed

NCT01219335

Discarded Materials Study

Recruiting

\) going through the adoption process, or

\) taking monophasic oral contraceptives for at least six months

You may not qualify if:

English not the primary language
Women who are peri- or post-menopausal
Women who are currently taking anti-depressants or have a history of head injury or neurological/psychiatric condition
Groups 1 \& 2 (IVF) - women who are undergoing Inter-uterine insemination as an infertility treatment
Group 3 (ADPT) - women who underwent hormonal infertility treatments within the previous 6 months
Group 4 (OC) - women on progesterone only (mini-pill) oral contraceptives

Contact the study team to confirm eligibility.

Oddens BJ, den Tonkelaar I, Nieuwenhuyse H. Psychosocial experiences in women facing fertility problems--a comparative survey. Hum Reprod. 1999 Jan;14(1):255-61. doi: 10.1093/humrep/14.1.255.

PMID: 10374131BACKGROUND

Study Completion

November 2006

Actual (reported)

Last Updated

December 11, 2009

Record last verified: 2006-11

Source record

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Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT00113867
Data provider: ClinicalTrials.gov
Source updated: 2009-12-11
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:29:13 UTC

Locations

US(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Keywords

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (3)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations