NCT00179348

Brief Summary

This clinical trial studies yoga-based rehabilitation in reducing physical and emotional side effects of living with cancer or its treatment. Yoga-based rehabilitation may reduce side effects and improve the quality of life of patients with breast, lung, or colorectal cancer.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
399

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2001

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 8, 2001

Completed
4.6 years until next milestone

First Submitted

Initial submission to the registry

September 13, 2005

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 16, 2005

Completed
10.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 20, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 20, 2016

Completed
Last Updated

May 31, 2023

Status Verified

May 1, 2023

Enrollment Period

15.5 years

First QC Date

September 13, 2005

Last Update Submit

May 28, 2023

Conditions

Outcome Measures

Primary Outcomes (3)

  • Change in Functional Assessment of Cancer Therapy summary score (physical, emotional, spiritual, and social QOL)

    A repeated measures analysis of covariance will be performed for each of the five patient groups. This analysis will examine between and within group differences at T2 and T3 assessment points, after controlling for baseline levels of QOL.

    Baseline to up to 6 months

  • Program compliance as measured by Yoga - Daily Practice Calendar and Yoga Class Attendance Record and Yoga Evaluation Form

    Descriptive analyses (percentages) will be conducted to examine levels of compliance (class attendance + home practice) for each patient group, self-identified ethnic group, and language of preference. Logistic regression analyses will be performed to identify patients in the top 25% for compliance based on sociocultural, medical, and lifestyle factors.

    Up to 6 months

  • Program satisfaction measured by Yoga - Daily Practice Calendar and Yoga Class Attendance Record and Yoga Evaluation Form

    Descriptive analyses (percentages) will be conducted to examine levels of satisfaction (total score on yoga evaluation form) for each patient group, self-identified ethnic group, and language of preference. Logistic regression analyses will be performed to identify patients in the top 25% for satisfaction based on sociocultural, medical, and lifestyle factors.

    Up to 6 months

Secondary Outcomes (3)

  • Pain

    Baseline to up to 6 months

  • Mood

    Baseline to up to 6 months

  • spiritual well-being

    Baseline to up to 6 months

Study Arms (2)

Group I (yoga-based rehabilitation program)

EXPERIMENTAL

Participants undergo a yoga-based rehabilitation program up to 5 days a week for 1.5 hours and practice at home at least once daily for 12 weeks.

Procedure: Quality-of-Life AssessmentProcedure: Yoga

Group II (standard care/control)

ACTIVE COMPARATOR

After a 3 month wait period, participants undergo a yoga-based rehabilitation program as in Group I.

Procedure: Quality-of-Life AssessmentProcedure: Yoga

Interventions

Ancillary studies

Also known as: Quality of Life Assessment
Group I (yoga-based rehabilitation program)Group II (standard care/control)
YogaPROCEDURE

Undergo a yoga-based rehabilitation program

Also known as: Yoga Therapy
Group I (yoga-based rehabilitation program)Group II (standard care/control)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Have been diagnosed with breast, lung or colorectal cancer in the previous 8 weeks
  • Are to receive oncologic care at the Albert Einstein Cancer Center (AECC)
  • Have a life-expectancy of at least 6 months
  • Are either English- or Spanish-speaking
  • Do not practice yoga regularly (\> 1 month)
  • Receive medical clearance by oncologic personnel on the study

You may not qualify if:

  • Eastern Cooperative Oncology Group performance status \>= 3
  • Existence of any of the following:
  • Seizure disorder
  • Musculoskeletal conditions
  • Heart problems
  • Major psychiatric disorder

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Albert Einstein College of Medicine

The Bronx, New York, 10461, United States

Location

Related Publications (1)

  • Moadel AB, Shah C, Wylie-Rosett J, Harris MS, Patel SR, Hall CB, Sparano JA. Randomized controlled trial of yoga among a multiethnic sample of breast cancer patients: effects on quality of life. J Clin Oncol. 2007 Oct 1;25(28):4387-95. doi: 10.1200/JCO.2006.06.6027. Epub 2007 Sep 4.

MeSH Terms

Conditions

AlopeciaAnxiety DisordersBreast NeoplasmsColorectal NeoplasmsDepressionFatigueLung NeoplasmsNauseaVomitingPainSleep Wake DisordersBody Weight Changes

Interventions

Yoga

Condition Hierarchy (Ancestors)

HypotrichosisHair DiseasesSkin DiseasesSkin and Connective Tissue DiseasesPathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsMental DisordersNeoplasms by SiteNeoplasmsBreast DiseasesIntestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal DiseasesRectal DiseasesBehavioral SymptomsBehaviorSigns and SymptomsRespiratory Tract NeoplasmsThoracic NeoplasmsLung DiseasesRespiratory Tract DiseasesSigns and Symptoms, DigestiveNeurologic ManifestationsNervous System DiseasesBody Weight

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsSpiritual TherapiesExercise Movement TechniquesPhysical Therapy Modalities

Study Officials

  • Alyson Moadel

    Albert Einstein College of Medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 13, 2005

First Posted

September 16, 2005

Study Start

February 8, 2001

Primary Completion

July 20, 2016

Study Completion

July 20, 2016

Last Updated

May 31, 2023

Record last verified: 2023-05

Locations