NCT02442635

Brief Summary

This proposal aims to expand non-pharmacologic options for the control of symptoms during chemotherapy using yoga practices. It is particularly focused on sleep disturbance with a secondary focus on fatigue.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
73

participants targeted

Target at P25-P50 for not_applicable cancer

Timeline
Completed

Started May 2015

Longer than P75 for not_applicable cancer

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 30, 2015

Completed
1 day until next milestone

Study Start

First participant enrolled

May 1, 2015

Completed
12 days until next milestone

First Posted

Study publicly available on registry

May 13, 2015

Completed
4.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2019

Completed
Last Updated

November 14, 2019

Status Verified

November 1, 2019

Enrollment Period

4.4 years

First QC Date

April 30, 2015

Last Update Submit

November 12, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Sleep Disturbance as measured by the General Sleep Disturbance Scale

    6 weeks

Secondary Outcomes (1)

  • Fatigue as measured by the Lee Fatigue Scale

    6 weeks

Other Outcomes (9)

  • Quality of Life as measured by the Multidimensional Quality of Life Scale--Cancer

    6 weeks

  • Depressive Symptoms as measured by the CES-D

    6 weeks

  • Anxiety as measured by the Spielberger State Anxiety Inventory

    6 weeks

  • +6 more other outcomes

Study Arms (3)

Condition 1

EXPERIMENTAL

Yoga Breathing

Behavioral: Yoga

Condition 2

EXPERIMENTAL

Static Yoga

Behavioral: Yoga

Condition 3

EXPERIMENTAL

Flowing Yoga

Behavioral: Yoga

Interventions

YogaBEHAVIORAL

Yoga breathing and postures; After this initial 3 arm experiment, yoga breathing and postures will be studied in combination.

Condition 1Condition 2Condition 3

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18 and older
  • Have a Karnofsky Performance Status Score of 60 or above
  • Diagnosed with any cancer except acute leukemia
  • Self-reported poor quality of sleep
  • Receiving Chemotherapy
  • Able to read, write, and understand English
  • Ability to give informed consent

You may not qualify if:

  • Diagnosed with brain metastasis
  • Diagnosed with severe Chronic Obstructive Pulmonary Disease (COPD) or emphysema
  • Have New York Heart Association class II or greater congestive heart failure
  • Requiring chronic home oxygen therapy
  • Diagnosed with a sleep disorder (e.g., sleep apnea or narcolepsy)
  • Have received more than 3 prior chemotherapy regimens
  • Receiving radiation therapy
  • Has a less than 6 month life expectancy
  • Regular yoga practice within the last 2 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UCSF

San Francisco, California, 94110, United States

Location

MeSH Terms

Conditions

NeoplasmsParasomniasFatigue

Interventions

Yoga

Condition Hierarchy (Ancestors)

Sleep Wake DisordersNervous System DiseasesMental DisordersSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Mind-Body TherapiesComplementary TherapiesTherapeuticsSpiritual TherapiesExercise Movement TechniquesPhysical Therapy Modalities

Study Officials

  • Anand Dhruva, MD

    University of California, San Francisco

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 30, 2015

First Posted

May 13, 2015

Study Start

May 1, 2015

Primary Completion

October 1, 2019

Study Completion

October 1, 2019

Last Updated

November 14, 2019

Record last verified: 2019-11

Data Sharing

IPD Sharing
Will not share

Locations