Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research

NCT00177268 | Recruiting

• 1 other identifier: STUDY19010322
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

This is a tissue, urine, and blood banking protocol for cutaneous t-cell lymphoma (CTCL), eczema, and atopic dermatitis patients for current and future research.

Conditions

Sezary Syndrome; Mycosis Fungoides; Eczema; Atopic Dermatitis; Cutaneous T-cell Lymphoma

Keywords

Cutaneous T-cell Lymphoma; Sezary Syndrome; Mycosis Fungoides; Blood/tissue banking; eczema; atopic dermatitis

Outcome Measures

Primary Outcomes (1)

• Proteomics of Cutaneous T-cell lymphoma

  Proteomic variables will be measured in blood and tissue of consented CTCL patients.

  Ongoing

Study Arms (1)

CTCL, atopic dermatitis, eczema

Those subjects with cutaneous t-cell lymphoma and Sezary syndrome, atopic dermatitis, or eczema may participate as appropriate with the potential for blood, tissue or urine sampling.

Other: Blood draw, skin biopsy or urine collection

Interventions

Blood draw, skin biopsy or urine collection OTHER

Up to 9 blood draws/year of 60 ml of whole blood. One 6 mm punch biopsy may be obtained up to 4 times per year.

CTCL, atopic dermatitis, eczema

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Subjects with cutaneous t-cell lymphoma and/or Sezary syndrome and atopic dermatitis or eczema patients

You may qualify if:

• or older
• able and willing to provide informed consent
• diagnosed with CTCL
• diagnosed with either atopic dermatitis or eczema

You may not qualify if:

• Lack of CTCL, atopic dermatitis, or eczema diagnosis in medical record

Sponsors & Collaborators

• University of Pittsburgh: lead

Study Sites (1)

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15213, United States

RECRUITING

Biospecimen

Retention: SAMPLES WITHOUT DNA

White blood cells and/or skin biopsy tissue are retained.

MeSH Terms

Conditions

Lymphoma, T-Cell, Cutaneous; Sezary Syndrome; Mycosis Fungoides; Eczema; Dermatitis, Atopic

Interventions

Blood Specimen Collection; Urine Specimen Collection

Condition Hierarchy (Ancestors)

Lymphoma, T-Cell; Lymphoma, Non-Hodgkin; Lymphoma; Neoplasms by Histologic Type; Neoplasms; Lymphoproliferative Disorders; Lymphatic Diseases; Hemic and Lymphatic Diseases; Immunoproliferative Disorders; Immune System Diseases; Dermatitis; Skin Diseases; Skin and Connective Tissue Diseases; Skin Diseases, Eczematous; Skin Diseases, Genetic; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hypersensitivity, Immediate; Hypersensitivity

Intervention Hierarchy (Ancestors)

Specimen Handling; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Punctures; Surgical Procedures, Operative; Investigative Techniques

Study Officials

• Oleg E Akilov, M.D., PhD

  University of Pittsburgh

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Charity L Ruhl, LPN

CONTACT

4126472013; ruhlcl@upmc.edu

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor of Dermatology

Study Record Dates

• First Submitted: September 12, 2005
• First Posted: September 15, 2005
• Study Start: October 1, 2004
• Primary Completion (Estimated): January 1, 2030
• Study Completion (Estimated): January 1, 2032
• Last Updated: December 30, 2025

Record last verified: 2025-12

Locations

US (1)