Key Insights

Highlights

Success Rate

77% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

12.5%

6 terminated out of 48 trials

Success Rate

76.9%

-9.6% vs benchmark

Late-Stage Pipeline

8%

4 trials in Phase 3/4

Results Transparency

50%

10 of 20 completed with results

Key Signals

10 with results77% success

Data Visualizations

Phase Distribution

37Total
Not Applicable (2)
Early P 1 (1)
P 1 (13)
P 2 (17)
P 3 (1)
P 4 (3)

Trial Status

Completed20
Recruiting9
Active Not Recruiting6
Terminated6
Unknown3
Not Yet Recruiting3

Trial Success Rate

76.9%

Benchmark: 86.5%

Based on 20 completed trials

Clinical Trials (48)

Showing 20 of 20 trials
NCT05377827Phase 1Active Not Recruiting

Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies

NCT07535710Phase 1Not Yet Recruiting

Aclarubicin Plus Cyclophosphamide, Vincristine, and Prednisone (CAOP) in Patients With Previously Treated Cutaneous T-cell Lymphoma

NCT02978625Phase 2Active Not Recruiting

Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers

NCT04960618Phase 2Active Not Recruiting

Pembrolizumab in Combination With Gemcitabine in People With Advanced Mycosis Fungoides or Sézary Syndrome

NCT07477769Not Yet RecruitingPrimary

Lymphocyte Phenotype of Autosomal Recessive Congenital Ichthyoses Mutated NIPAL4 (Nipal4-nEDD)

NCT05944562Phase 1Active Not Recruiting

Tulmimetostat (DZR123) in Patients With Mycosis Fungoides and Sézary Syndrome

NCT03602157Phase 1Active Not Recruiting

Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL

NCT00177268Recruiting

Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis Research

NCT05157581RecruitingPrimary

Extracorporeal Photopheresis in Sezary Syndrome

NCT02840747Recruiting

Tissue Repository: CTCL Collection Protocol

NCT03587844Phase 2Recruiting

Dosing of Brentuximab Vedotin for Mycosis Fungoides, Sezary Syndrome Patients

NCT04541017Phase 1Terminated

Testing the Addition of an Anti-cancer Drug, Hu5F9-G4 (Magrolimab), to the Usual Chemotherapy Treatment (Mogamulizumab) in T-Cell (a Type of Immune Cell) Lymphoma That Has Returned After Treatment or Does Not Respond to Treatment

NCT04930653Phase 2Recruiting

Extracorporeal Photopheresis and Mogamulizumab for the Treatment of Erythrodermic Cutaneous T Cell Lymphoma

NCT07213882Early Phase 1Not Yet Recruiting

A Phase 1, Multicenter, Open-label, Prospective, First-in-human Dose-escalation Clinical Trial of Domain Therapeutics' Anti-CCR8 Monoclonal Antibody (DT-7012) in Patients With Relapsed or Refractory Cutaneous T-cell Lymphomas (CTCL)

NCT07132567Recruiting

Assessment of Safety and Efficacy of Poteligeo Inj. 20 mg (Mogamulizumab) Through Use-result Surveillance

NCT03011814Phase 1Active Not Recruiting

Durvalumab With or Without Lenalidomide in Treating Patients With Relapsed or Refractory Cutaneous or Peripheral T Cell Lymphoma

NCT03695471Phase 2Completed

Pembrolizumab in Treating Patients With Stage IB-IV Mycosis Fungoides

NCT05879458Phase 2Terminated

Ritlecitinib in CTCL

NCT04256018Phase 2RecruitingPrimary

Mogamulizumab + Low-Dose Total Skin Electron Beam Tx in Mycosis Fungoides & Sézary Syndrome

NCT05978141Recruiting

A Registry for People With T-cell Lymphoma

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Research Network

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