NCT00175942

Brief Summary

Sudden cardiac death is in most cases triggered by ischemia-related ventricular tachyarrhythmias and accounts for 50% of deaths from cardiovascular disease in developed countries. Chronic elevation of indicators of coagulation activation has been found in patients with coronary heart disease , but a role of coagulation activation and proinflammatory state as a potential risk factor for ventricular fibrillation (VF) during acute myocardial infarction has not been investigated.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
300

participants targeted

Target at P75+ for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2003

Completed
2.6 years until next milestone

First Submitted

Initial submission to the registry

September 10, 2005

Completed
5 days until next milestone

First Posted

Study publicly available on registry

September 15, 2005

Completed
Last Updated

September 15, 2005

Status Verified

May 1, 2005

First QC Date

September 10, 2005

Last Update Submit

September 10, 2005

Conditions

Acute Myocardial InfarctionSudden Cardiac Death

Keywords

acute myocardial infarctionventricular fibrillationcoagulationinflammation

Eligibility Criteria

Age0 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • ST-elevation myocardial infarction ventricular fibrillation during acute MI

You may not qualify if:

  • NSTEMI coagulation disorders, e.g.intake of coumadin

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital of Mannheim, University of Heidelberg

Mannheim, 68167, Germany

RECRUITING

MeSH Terms

Conditions

Death, Sudden, CardiacVentricular FibrillationThrombosisInflammation

Condition Hierarchy (Ancestors)

Heart ArrestHeart DiseasesCardiovascular DiseasesDeath, SuddenDeathPathologic ProcessesPathological Conditions, Signs and SymptomsArrhythmias, CardiacEmbolism and ThrombosisVascular Diseases

Study Officials

  • Carl E. Dempfle, Prof.Dr.

    University Hospital of Mannheim, University of Heidelberg

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Elif Elmas, MD, Dr.

CONTACT

00496213833988

Martina Brückmann, MD, Dr.

CONTACT

Study Design

Study Type
observational
Observational Model
DEFINED POPULATION
Time Perspective
OTHER
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 10, 2005

First Posted

September 15, 2005

Study Start

February 1, 2003

Last Updated

September 15, 2005

Record last verified: 2005-05

Locations

DE(1)