NCT00752713

Brief Summary

The aim of the study was therefore to evaluate whether myocardial deformation imaging performed by SENC allows for quantification of regional left ventricular function and is related to transmurality states of infarcted tissue in patients with acute myocardial infarction (AMI).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jan 2007

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2007

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2008

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

September 11, 2008

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 15, 2008

Completed
Last Updated

September 16, 2008

Status Verified

September 1, 2008

Enrollment Period

1 year

First QC Date

September 11, 2008

Last Update Submit

September 15, 2008

Conditions

Acute Myocardial Infarction

Keywords

AMI,Reperfusionsuccessful

Outcome Measures

Primary Outcomes (1)

  • Left ventricular function

    01.01.2007 until 01.02.2007

Secondary Outcomes (1)

  • Transmurality

    01.01.2007 until 01.02.2007

Study Arms (2)

1

Patients presenting to hospital with AMI

Procedure: cardiac MRI

2

healthy volunteers as control group

Procedure: cardiac MRI

Interventions

cardiac MRIPROCEDURE

cardiac MRI at one time point for group 1 after intervention for group 2 at any time point

Also known as: cardiac resonance magnetic imaging
12

Eligibility Criteria

Age30 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

* Consecutive Patients with AMI 3+/-1 days after successful reperfusion * Ten healthy volunteers serving as control group

You may qualify if:

  • Patients with AMI after successful reperfusion
  • Healthy volunteers in control group

You may not qualify if:

  • No reperfusion

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Heidelberg

Heidelberg, 69120, Germany

Location

Related Publications (1)

  • Neizel M, Korosoglou G, Lossnitzer D, Kuhl H, Hoffmann R, Ocklenburg C, Giannitsis E, Osman NF, Katus HA, Steen H. Impact of systolic and diastolic deformation indexes assessed by strain-encoded imaging to predict persistent severe myocardial dysfunction in patients after acute myocardial infarction at follow-up. J Am Coll Cardiol. 2010 Sep 21;56(13):1056-62. doi: 10.1016/j.jacc.2010.02.070.

    PMID: 20846606DERIVED

Study Officials

  • Mirja Neizel, MD

    University Hospital Heidelberg

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 11, 2008

First Posted

September 15, 2008

Study Start

January 1, 2007

Primary Completion

January 1, 2008

Study Completion

January 1, 2008

Last Updated

September 16, 2008

Record last verified: 2008-09

Locations

DE(1)