NCT00166049

Brief Summary

The purpose of the Education and Supportive Partners Improving Self-Care (ENSPIRE) study is to compare the effect of a Family Partnership Intervention (FPI) over patient and family education and usual heart failure care on physical and mental health outcomes over an 8-month period. The study will examine three ways of giving heart failure patients and their family members information. This study will help scientists determine if learning these communication skills will help people with heart failure to better manage their symptoms and improve their health outcomes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
170

participants targeted

Target at P50-P75 for not_applicable heart-failure

Timeline
Completed

Started Apr 2005

Longer than P75 for not_applicable heart-failure

Geographic Reach
1 country

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2005

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

August 31, 2005

Completed
14 days until next milestone

First Posted

Study publicly available on registry

September 14, 2005

Completed
5.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2011

Completed
Last Updated

November 11, 2015

Status Verified

September 1, 2013

Enrollment Period

6.1 years

First QC Date

August 31, 2005

Last Update Submit

November 9, 2015

Conditions

Keywords

Heart failureFamily partnershipPatient family education

Outcome Measures

Primary Outcomes (4)

  • Adherence to dietary sodium and medication taking behavior

    4 and 8 months after baseline enrollment.

  • Physical status: 6-minute walk and brain natriuretic peptide

    4 and 8 months after baseline enrollment.

  • Psychological status: depressive symptoms

    4 and 8 months after baseline enrollment.

  • Health related quality of life

    4 and 8 months after baseline enrollment.

Secondary Outcomes (4)

  • Health resource utilization (HRUQ)

    4 and 8 months after baseline enrollment.

  • Autonomy support (AS)

    4 and 8 months after baseline enrollment.

  • Perceived family criticism

    4 and 8 months after baseline enrollment.

  • Knowledge

    4 and 8 months after baseline enrollment.

Study Arms (3)

Usual Care Attention Control

PLACEBO COMPARATOR

Usual care with provision of supplemental printed educational material on HF self care

Behavioral: Usual care with educational material

Group 2 Patient Family Education PFE

EXPERIMENTAL

Patient Family Education PFE Heart Failure Patients and family member dyads were provided with an educational and counseling session, and attended a 2 hour patient-family education session on heart failure self management with emphasis on dietary sodium and medication taking behaviors.

Behavioral: Patient and Family EducationBehavioral: Usual care with educational material

Group 3 Family Partnership Intervention

EXPERIMENTAL

Patient and family member received one individual dyadic education/counseling session, and two group sessions focused on developing family approaches to HF self management. the emphasis of the two group sessions was on developing autonomy supportive approaches to family support.

Behavioral: Family Partnership Intervention (FPI)Behavioral: Patient and Family EducationBehavioral: Usual care with educational material

Interventions

HF patient and family receive structured patient and family education sessions plus intervention to improve family communication one month after enrollment.Patient and family member received one individual dyadic education/counseling session after baseline data collection, and two group sessions (2-3 months after baseline) focused on developing family approaches to HF self management.Telephone counseling for the dyad and reinforcing mailed newsletters at 5-6 months after baseline.

Group 3 Family Partnership Intervention

HF Patient and one family member receive structured education sessions one month after enrollment.Two sessions, one indivdual with patient-family member dyad after baseline, and one in a group setting between 2-3 months after baseline. The group session was 2 hours in duration. Telephone counseling for the dyad ast 5-6 months, mailed newsletters at Mailed newsletters at 5-6 months.

Also known as: Patient Family Education PFE
Group 2 Patient Family Education PFEGroup 3 Family Partnership Intervention

Usual care with provision of printed educational material, provided once at baseline

Also known as: Usual Care Attention Control
Group 2 Patient Family Education PFEGroup 3 Family Partnership InterventionUsual Care Attention Control

Eligibility Criteria

Age21 Years - 79 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Documented diagnosis of heart failure (New York Heart Association \[NYHA\] Class II or III)
  • Aged 21-79
  • Currently taking angiotensin-converting enzyme (ACE) inhibitor and diuretic medications
  • Recommended to exercise and low sodium diet
  • Willing to participate in educational sessions with a family member
  • Willing to spend a minimum of 9 hours and a maximum of 15 hours over an 8-month period
  • Willing to travel to either Emory University Hospital or Grady Memorial Hospital General Clinical Research Center (GCRC) for study activities

You may not qualify if:

  • NYHA Class I or IV heart failure
  • Heart attack within the last 6 months
  • Kidney failure
  • Significant angina/chest pain
  • Inability to read and write English

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Grady Hospital

Atlanta, Georgia, 30303, United States

Location

Crawford Long Hospital

Atlanta, Georgia, 30308, United States

Location

Emory University Hospital

Atlanta, Georgia, 30322, United States

Location

Atlanta Veterans Affairs (VA) Medical Center

Decatur, Georgia, 30033, United States

Location

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • Sandra B. Dunbar, RN, DSN

    Emory University School of Nursing

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor, Emory University, Nell Hodgson Woodruff School of Nursing

Study Record Dates

First Submitted

August 31, 2005

First Posted

September 14, 2005

Study Start

April 1, 2005

Primary Completion

May 1, 2011

Study Completion

May 1, 2011

Last Updated

November 11, 2015

Record last verified: 2013-09

Locations