A Comparison of Weighted Vest Exercise and Strength Training

NCT00158119 | Completed Phase 3

• 2 other identifiers: AG0037K23AG019663-01
• Study Type: interventional
• Target: 160
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to evaluate two types of exercise therapy designed to improve muscle power and mobility: weighted vest exercise vs. progressive resistance training.

Conditions

Mobility Limitations; Aging

Keywords

strength training; power training; exercise training; functional performance tasks

Outcome Measures

Primary Outcomes (5)

• Leg power

• leg strength

• mobility

• endurance

• balance measured at baseline, 8 weeks, and 16 weeks

Secondary Outcomes (1)

• Disability

Interventions

InVEST (Increased Velocity Exercise Specific to Task) BEHAVIORAL

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• Community dwelling men and women aged 65 or older
• Ability to provide informed consent
• Impairment in physical performance, based on a score between 4 and 10 inclusive on the SPPB (Short Physical Performance Battery), which evaluates standing balance, walking speed, and chair-rise time
• Score of 24 or greater on the Folstein mini-mental status exam
• Exhibit independent stair-climbing ability

You may not qualify if:

• Unstable acute or chronic disease
• Neuromusculoskeletal impairment interfering with independent stair climbing
• Abdominal aortic aneurysm
• Exertional angina
• History of ventricular arrhythmia
• Inguinal or abdominal hernia
• Symptomatic valvular heart disease

Sponsors & Collaborators

• National Institute on Aging (NIA): lead
• Spaulding Rehabilitation Hospital PM&R: collaborator

Study Sites (1)

Spaulding Cambridge Outpatient Center

Cambridge, Massachusetts, 02138, United States

Location

Related Publications (10)

• Bean JF, Kiely DK, Herman S, Leveille SG, Mizer K, Frontera WR, Fielding RA. The relationship between leg power and physical performance in mobility-limited older people. J Am Geriatr Soc. 2002 Mar;50(3):461-7. doi: 10.1046/j.1532-5415.2002.50111.x.

  PMID: 11943041 BACKGROUND

• Bean J, Herman S, Kiely DK, Callahan D, Mizer K, Frontera WR, Fielding RA. Weighted stair climbing in mobility-limited older people: a pilot study. J Am Geriatr Soc. 2002 Apr;50(4):663-70. doi: 10.1046/j.1532-5415.2002.50160.x.

  PMID: 11982666 BACKGROUND

• Fielding RA, LeBrasseur NK, Cuoco A, Bean J, Mizer K, Fiatarone Singh MA. High-velocity resistance training increases skeletal muscle peak power in older women. J Am Geriatr Soc. 2002 Apr;50(4):655-62. doi: 10.1046/j.1532-5415.2002.50159.x.

  PMID: 11982665 BACKGROUND

• Bean JF, Herman S, Kiely DK, Frey IC, Leveille SG, Fielding RA, Frontera WR. Increased Velocity Exercise Specific to Task (InVEST) training: a pilot study exploring effects on leg power, balance, and mobility in community-dwelling older women. J Am Geriatr Soc. 2004 May;52(5):799-804. doi: 10.1111/j.1532-5415.2004.52222.x.

  PMID: 15086665 BACKGROUND

• Bean JF, Vora A, Frontera WR. Benefits of exercise for community-dwelling older adults. Arch Phys Med Rehabil. 2004 Jul;85(7 Suppl 3):S31-42; quiz S43-4. doi: 10.1016/j.apmr.2004.03.010.

  PMID: 15221722 BACKGROUND

• Li X, Forman DE, Kiely DK, LaRose S, Hirschberg R, Frontera WR, Bean JF. Validity of an exercise test based on habitual gait speed in mobility-limited older adults. Arch Phys Med Rehabil. 2012 Feb;93(2):344-50. doi: 10.1016/j.apmr.2011.08.032.

  PMID: 22289248 DERIVED

• Suri P, Kiely DK, Leveille SG, Frontera WR, Bean JF. Increased trunk extension endurance is associated with meaningful improvement in balance among older adults with mobility problems. Arch Phys Med Rehabil. 2011 Jul;92(7):1038-43. doi: 10.1016/j.apmr.2010.12.044. Epub 2011 Jun 2.

  PMID: 21636073 DERIVED

• Bean JF, Kiely DK, LaRose S, Goldstein R, Frontera WR, Leveille SG. Are changes in leg power responsible for clinically meaningful improvements in mobility in older adults? J Am Geriatr Soc. 2010 Dec;58(12):2363-8. doi: 10.1111/j.1532-5415.2010.03155.x.

  PMID: 21143443 DERIVED

• Suri P, Kiely DK, Leveille SG, Frontera WR, Bean JF. Trunk muscle attributes are associated with balance and mobility in older adults: a pilot study. PM R. 2009 Oct;1(10):916-24. doi: 10.1016/j.pmrj.2009.09.009.

  PMID: 19854420 DERIVED

• Bean JF, Kiely DK, LaRose S, O'Neill E, Goldstein R, Frontera WR. Increased velocity exercise specific to task training versus the National Institute on Aging's strength training program: changes in limb power and mobility. J Gerontol A Biol Sci Med Sci. 2009 Sep;64(9):983-91. doi: 10.1093/gerona/glp056. Epub 2009 May 4.

  PMID: 19414509 DERIVED

MeSH Terms

Conditions

Mobility Limitation

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Jonathan F. Bean, MD, MS

  Spaulding Cambridge Outpatient Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 3
• Allocation: RANDOMIZED
• Masking: SINGLE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: NIH

Study Record Dates

• First Submitted: September 7, 2005
• First Posted: September 12, 2005
• Study Start: July 1, 2001
• Primary Completion: September 1, 2007
• Study Completion: September 1, 2007
• Last Updated: July 26, 2010

Record last verified: 2010-07

Locations

US (1)