Effectiveness of Family-Based Versus Individual Psychotherapy in Treating Adolescents With Anorexia Nervosa
Treatment of Adolescents With Anorexia Nervosa
2 other identifiers
interventional
120
1 country
1
Brief Summary
This study will compare the effectiveness of family-based therapy versus individual psychotherapy for the treatment of adolescent anorexia nervosa.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_1
Started Oct 2004
Longer than P75 for phase_1
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2004
CompletedFirst Submitted
Initial submission to the registry
September 6, 2005
CompletedFirst Posted
Study publicly available on registry
September 8, 2005
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2008
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2009
CompletedApril 10, 2012
April 1, 2012
3.4 years
September 6, 2005
April 9, 2012
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Scores on the Eating Disorders Examination
Measured at Year 1 of treatment and Year 1 of follow-up
Study Arms (2)
1
EXPERIMENTALThose adolescents receiving family based therapy
2
ACTIVE COMPARATORThose adolescents receiving individual therapy
Interventions
Family therapy will be given for a total of 24 hours over the course of 12 months.
Individual therapy will be given for a total of 24 hours over the course of 12 months.
Eligibility Criteria
You may qualify if:
- Meets DSM-IV criteria for anorexia nervosa
- Lives with at least one parent who is willing to participate
- Medically stable
- Adequate transportation to clinic
- Proficient at speaking, reading, and writing English
You may not qualify if:
- Currently undergoing treatment or taking medication that may affect eating or weight
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Stanford Universitylead
- National Institute of Mental Health (NIMH)collaborator
Study Sites (1)
The University of Chicago, Pritzker School of Medicine
Chicago, Illinois, 60637, United States
Related Publications (2)
Le Grange D, Lock J, Accurso EC, Agras WS, Darcy A, Forsberg S, Bryson SW. Relapse from remission at two- to four-year follow-up in two treatments for adolescent anorexia nervosa. J Am Acad Child Adolesc Psychiatry. 2014 Nov;53(11):1162-7. doi: 10.1016/j.jaac.2014.07.014. Epub 2014 Aug 23.
PMID: 25440306DERIVEDLock J, Le Grange D, Agras WS, Moye A, Bryson SW, Jo B. Randomized clinical trial comparing family-based treatment with adolescent-focused individual therapy for adolescents with anorexia nervosa. Arch Gen Psychiatry. 2010 Oct;67(10):1025-32. doi: 10.1001/archgenpsychiatry.2010.128.
PMID: 20921118DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
James D. Lock, MD, PhD
Stanford University
Study Design
- Study Type
- interventional
- Phase
- phase 1
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 6, 2005
First Posted
September 8, 2005
Study Start
October 1, 2004
Primary Completion
March 1, 2008
Study Completion
March 1, 2009
Last Updated
April 10, 2012
Record last verified: 2012-04