Pilot Study on Interferon Gamma in Association With Peg-Interferon Alpha 2a and Ribavirin Among Patients With a Chronic Hepatitis C and Non Responders to the Association of Peg-Interferon Alpha 2b or 2a and Ribavirin ANRS HC16 Gammatri
Sponsor study identifier
Secondary identifiers
NIH
interventional
65
1 country
2
Study Start
June 2004
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Not reported
Date not reportedStudy Completion
August 2007
Actual (reported)Viral hepatitis C is treated with peg-interferon alpha 2a/2b and ribavirin. There is no treatment recommended for non responders patients. This study will evaluate the efficacy, after a second treatment with peg-interferon alpha 2a and ribavirin for 12 Weeks of the addition of interferon gamma in non responders patients
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
August 2007
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
June 2004
Date type not reportedThis date has not been verified as actual or estimated.
September 7, 2005
Actual (reported)September 8, 2005
Actual (reported)August 2007
Actual (reported)Virological response as defined by an HCV RNA measure non detectable at W28 with qualitative PCR (centralized measure)
Virological response at W72
Biochemical response at W72 (ALT below normal value)
Quality of life
Immunologic response (CD4 and CD8 HCV specific)
Safety
Hopital Haut Leveque Service d'Hepato-Gastro-Enterologie
Pessac, 33604, France
Hôpital du Haut-Levêque
Pessac, 33604, France
Couzigou P, Perusat S, Bourliere M, Trimoulet P, Poynard T, Leroy V, Marcellin P, Foucher J, Bronowicki JP, Chene G; ANRS HC16 GAMMATRI Trial Group. Interferon-gamma with peginterferon alpha-2a and ribavirin in nonresponder patients with chronic hepatitis C (ANRS HC16 GAMMATRI). J Gastroenterol Hepatol. 2013 Feb;28(2):329-34. doi: 10.1111/jgh.12060.
Patrice Couzigou, MD, PhD
Hôpital du Haut-Lévêque, Pessac, France
Geneviève Chêne, MD, PhD
INSERM U593, Bordeaux, France
First Submitted
September 7, 2005
First Posted
September 8, 2005
Study Start
June 2004
Date type not reportedThis date has not been verified as actual or estimated.
Study Completion
August 2007
Actual (reported)Contact the study team to confirm eligibility.
Last Updated
August 30, 2007
Record last verified: 2007-08
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