Key Insights

Highlights

Success Rate

88% trial completion (above average)

Published Results

184 trials with published results (45%)

Research Maturity

311 completed trials (77% of total)

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 27/100

Termination Rate

10.1%

41 terminated out of 405 trials

Success Rate

88.4%

+1.8% vs benchmark

Late-Stage Pipeline

36%

144 trials in Phase 3/4

Results Transparency

59%

184 of 311 completed with results

Key Signals

184 with results88% success41 terminated

Data Visualizations

Phase Distribution

296Total
Not Applicable (21)
Early P 1 (1)
P 1 (42)
P 2 (88)
P 3 (71)
P 4 (73)

Trial Status

Completed311
Terminated41
Unknown34
Withdrawn11
Active Not Recruiting4
Recruiting2

Trial Success Rate

88.4%

Benchmark: 86.5%

Based on 311 completed trials

Clinical Trials (405)

Showing 20 of 20 trials
NCT04943588CompletedPrimary

Treating Hepatitis C in Pakistan. Strategies to Avoid Resistance to Antiviral Drugs

NCT05397067Not ApplicableCompletedPrimary

Linkage to Care for Persons With Hep C Infection

NCT03520660Phase 4Active Not Recruiting

People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents

NCT07037277Phase 3Active Not Recruiting

C-Forward: Efficacy and Safety of BEM/RZR vs SOF/VEL in Subjects With Chronic HCV

NCT00148837Phase 2CompletedPrimary

Efficacy of Prazosin Versus Placebo Associated With Peg-interferon Alpha 2b and Ribavirin in Chronic Hepatitis C With Genotype 1 or 4 and Severe Fibrosis

NCT04014179Not ApplicableCompleted

Enhancing Hepatitis C Testing and Treatment Among People Who Inject Drugs Attending Needle and Syringe Programs

NCT00221650Phase 2Completed

Treatment of Chronic Hepatitis C With PEG Interferon alfa2a and Ribavirin in HIV-infected Patients

NCT07298577Not ApplicableEnrolling By Invitation

Use of Gender, Age, Alfa-fetoprotein (AFP), and Des-gamma-carboxyprothrombin (PIVKA-II) or GAAD Score in Addition to Ultrasound for Surveillance of People At-risk for Developing Hepatocellular Carcinoma in Asia in Order to Detect Early Liver Cancer

NCT05140941Phase 4Active Not RecruitingPrimary

Sofosbuvir/Velpatasvir Treatment of Chronic Hepatitis C During Pregnancy

NCT00265642Phase 3CompletedPrimary

Evaluation of Irbesartan on Hepatic Fibrosis in Chronic Hepatitis C

NCT02771405Phase 3CompletedPrimary

Impact of Interferon Free Regimens in Patients With Chronic HCV and Successfully Treated HCC

NCT01332955Phase 2CompletedPrimary

Telaprevir in HIV-HCV Coinfected Patients Who Had Previously Failed a Peginterferon-Ribavirin Regimen

NCT05904470Phase 2Completed

A Phase 2, Safety and Efficacy of Bemnifosbuvir (BEM) and Ruzasvir (RZR) in Subjects With Chronic HCV

NCT03155906Not ApplicableCompletedPrimary

Integrated Treatment of Hepatitis C Virus Infection

NCT03987503Phase 4CompletedPrimary

The No One Waits Study: Acceptability and Feasibility of Community-based Point-of-diagnosis HCV Treatment Study

NCT02262728Phase 2CompletedPrimary

An Efficacy, Safety and Pharmacokinetics Study of Simeprevir, Daclatasvir and Sofosbuvir in Participants With Chronic Hepatitis C Virus Genotype 1 or 4 Infection and Decompensated Liver Disease

NCT04382404Phase 1CompletedPrimary

Treatment of Chronic Hepatitis C During Pregnancy With Sofosbuvir/Velpatasvir

NCT01353911Phase 2CompletedPrimary

Grazoprevir (MK-5172) Administered With Peginterferon and Ribavirin in Treatment-Naïve Participants With Chronic Hepatitis C (MK-5172-003)

NCT01440595Phase 2TerminatedPrimary

Grazoprevir (MK-5172) With Peg-Interferon and Ribavirin in Participants With Chronic Genotype 2 or 3 Hepatitis C (MK-5172-012)

NCT06373198Not Yet RecruitingPrimary

Implementation of a Re-engagement Program for Hepatitis C Patients Lost to Follow-up in Argentina.

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