Proteomic Profiling for Influenza

You may not qualify if:

• Subject received an influenza vaccine 6 months preceding enrollment in the study.
• Subject had physician-diagnosed (preferably by culture) influenza at any time during the past 2 years.
• Subject had an acute illness with or without fever (temperature greater than or equal to 99.5ºF \[oral\]) in the 72 hours preceding vaccination.
• Subject received any vaccine 14 days before enrollment or plans to receive any vaccine during this study.
• Subject received blood or blood products in the last 3 months.
• Subject has known or suspected disease(s) of the immune system (ie, rheumatoid arthritis, lupus, lymphoma, human immunodeficiency virus, etc). Stable, controlled osteoarthritis is allowed if medication is only intermittently used for relief of symptoms.
• Subject has underlying unstable chronic disease such as uncontrolled hypertension (systolic blood pressure \>180 mm Hg or diastolic blood pressure \>100 mm Hg at Visit 1), congestive heart failure, heart attack within the last 6 months, liver, and kidney disease, etc;
• Subject is currently being treated with an immunosuppressive medications (i.e., cancer therapeutic agents such as Tamoxifen, systemic corticosteroids such as Prednisone, and arthritis medications such as Methotrexate). Please note that inhaled or topical corticosteriods are acceptable.
• Subject is pregnant or planning to become pregnant within the next 2 months.
• Subject is breastfeeding.
• Subject has a history of allergic disease or reactions likely to be exacerbated by any component of the study vaccine, including a history of anaphylaxis or serious vaccine reaction; subject is allergic to eggs, contact lens solution, or has ever had a severe reaction to any influenza vaccine.
• Subject is allergic to latex rubber;
• Subject has any condition that would, in the opinion of the site investigator, place the subject at an unacceptable risk of injury or render the subject unable to meet the requirements of the protocol.
• Subject has acute respiratory or other active infections or illnesses.
• Subject has any active neurologic disorders (ie, encephalopathy, optic neuritis/neuropathy, partial facial paralysis, and brachial plexus neuropathy).
• +2 more criteria