Strategies to Reduce Weight Gain in Hypertensive Smokers

Nicotine Patch in dosages given based on number of cigarettes per day smoked. 21 mg patch, 14 mg patch, 7 mg patch for total of 6 weeks duration of therapy. NRT gum is being provided to assist with relapse prevention. At the randomization visit the participant is given one (1) box of 2mg NRT gum, which consists of (110) pieces. The participant may request up to two (2) more boxes, for a maximum of three (3) boxes per participant.

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

You may not qualify if:

• Inability to understand consent procedures
• History of an allergic reaction to nicotine replacement therapy
• History of atopic or eczematous dermatitis
• Chronic or severe dermatosis
• History of unstable heart disease, including heart attack, stroke, and unstable angina in the 6 months prior to study entry
• Coronary artery bypass grafting or angioplasty/stent in the 3 months prior to study entry
• Cardiac dysrhythmia (except atrial fibrillation) treated with anti-arrhythmia medication
• History of congestive heart failure (NYHA Class III or IV)
• ECG evidence of 2nd or 3rd degree AV block
• Uncontrolled or stage II hypertension, defined as blood pressure typically greater than 160/100 mm Hg
• History of severe kidney or liver failure
• Current substance abuse (includes alcohol use in excess of 21 drinks a week)
• Severe COPD
• Insulin-dependent diabetes mellitus
• Fasting blood sugar greater than 160 mg/dl
• +13 more criteria

Contact the study team to confirm eligibility.