A Phase II Study of Methotrexate and Thiotepa Chemotherapy for Patients With Newly Diagnosed Primary CNS Lymphoma
Sponsor study identifier
Secondary identifiers
interventional
N/A
1 country
9
Study Start
October 2002
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Not reported
Date not reportedStudy Completion
January 2006
Actual (reported)RATIONALE: Drugs used in chemotherapy, such as methotrexate and thiotepa, work in different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining methotrexate with thiotepa in treating patients who have newly-diagnosed primary CNS lymphoma.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
January 2006
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 6, 2002
Actual (reported)October 2002
Date type not reportedThis date has not been verified as actual or estimated.
January 27, 2003
Actual (reported)January 2006
Actual (reported)Complete radiographic response
Duration of progression-free survival and overall survival
Toxicity
Association of tumor BCL-6 expression with response
Relationship among initial response to steroids, response to chemotherapy, and survival
Comprehensive Cancer Center at University of Alabama at Birmingham
Birmingham, Alabama, 35294-3410, United States
H. Lee Moffitt Cancer Center and Research Institute at University of South Florida
Tampa, Florida, 33612-9497, United States
Winship Cancer Institute of Emory University
Atlanta, Georgia, 30322, United States
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland, 21231-2410, United States
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114, United States
Josephine Ford Cancer Center at Henry Ford Hospital
Detroit, Michigan, 48202, United States
Tracy Batchelor, MD, MPH
Massachusetts General Hospital
First Submitted
September 6, 2002
First Posted
January 27, 2003
Study Start
October 2002
Date type not reportedThis date has not been verified as actual or estimated.
Study Completion
January 2006
Actual (reported)Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.
Comprehensive Cancer Center at Wake Forest University
Winston-Salem, North Carolina, 27157-1096, United States
Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio, 44195, United States
Abramson Cancer Center of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104-4283, United States
Last Updated
June 24, 2013
Record last verified: 2005-12
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: